Host lipidome analysis during rhinovirus replication in HBECs identifies potential therapeutic targets

In patients with asthma or chronic obstructive pulmonary disease, rhinovirus (RV) infections can provoke acute worsening of disease, and limited treatment options exist. Viral replication in the host cell induces significant remodeling of intracellular membranes, but few studies have explored this m...

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Bibliographic Details
Published in:	Journal of lipid research Vol. 59; no. 9; pp. 1671 - 1684
Main Authors:	Nguyen, An, Guedán, Anabel, Mousnier, Aurelie, Swieboda, Dawid, Zhang, Qifeng, Horkai, Dorottya, Le Novere, Nicolas, Solari, Roberto, Wakelam, Michael J O
Format:	Journal Article
Language:	English
Published:	United States Elsevier 01.09.2018
Subjects:	Antiviral Agents - pharmacology Bronchi - cytology ceramidase Epithelial Cells - metabolism Epithelial Cells - virology fatty acid synthase HeLa Cells human bronchial epithelial cells Humans Lipid Metabolism - drug effects lipidomics Molecular Targeted Therapy Rhinovirus - drug effects Rhinovirus - physiology Virus Replication ceramidase human bronchial epithelial cells fatty acid synthase lipidomics
ISSN:	1539-7262, 0022-2275, 1539-7262
Online Access:	Get full text
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