Direct effects of glucagon on glucose uptake and lipolysis in human adipocytes

We aim to investigate the expression of the glucagon receptor (GCGR) in human adipose tissue, and the impact of glucagon in glucose uptake and lipolysis in human adipocytes. GCGR gene expression in human subcutaneous and visceral adipose tissue was demonstrated, albeit at low levels and with an inte...

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Veröffentlicht in:	Molecular and cellular endocrinology Jg. 503; S. 110696
Hauptverfasser:	Pereira, Maria J., Thombare, Ketan, Sarsenbayeva, Assel, Kamble, Prasad G., Almby, Kristina, Lundqvist, Martin, Eriksson, Jan W.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Ireland Elsevier B.V 01.03.2020
Schlagworte:	adipocytes Adipocytes - drug effects Adipocytes - metabolism Adipocytes - pathology Adipose tissue Adipose Tissue - metabolism Adipose Tissue - pathology Adult Aged body mass index Carbohydrate Metabolism - drug effects Case-Control Studies Cells, Cultured Cohort Studies Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - pathology Female gene expression Gene Expression - drug effects genes Glucagon Glucagon - pharmacology Glucagon receptor glucagon receptors glucose Glucose - metabolism Glucose uptake Humans insulin insulin resistance Lipolysis Lipolysis - drug effects Male Metabolism Middle Aged Primary Cell Culture Receptors, Glucagon - genetics Receptors, Glucagon - metabolism Glucose uptake Glucagon receptor Adipose tissue Glucagon Metabolism Lipolysis
ISSN:	0303-7207, 1872-8057, 1872-8057
Online-Zugang:	Volltext
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