Cervical cancer: A global health crisis

Cervical cancer is the fourth most common malignancy diagnosed in women worldwide. Nearly all cases of cervical cancer result from infection with the human papillomavirus, and the prevention of cervical cancer includes screening and vaccination. Primary treatment options for patients with cervical c...

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Bibliographic Details
Published in:Cancer Vol. 123; no. 13; pp. 2404 - 2412
Main Authors: Small, William, Bacon, Monica A., Bajaj, Amishi, Chuang, Linus T., Fisher, Brandon J., Harkenrider, Matthew M., Jhingran, Anuja, Kitchener, Henry C., Mileshkin, Linda R., Viswanathan, Akila N., Gaffney, David K.
Format: Journal Article
Language:English
Published: United States Wiley Subscription Services, Inc 01.07.2017
Subjects:
activism
Adenocarcinoma, Clear Cell - pathology
Adenocarcinoma, Clear Cell - therapy
Antineoplastic Agents - therapeutic use
Biology
Brachytherapy
Cancer
Cancer therapies
Carcinoma, Adenosquamous - pathology
Carcinoma, Adenosquamous - therapy
Carcinoma, Neuroendocrine - pathology
Carcinoma, Neuroendocrine - therapy
Carcinoma, Small Cell - pathology
Carcinoma, Small Cell - therapy
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - prevention & control
Carcinoma, Squamous Cell - therapy
Carcinoma, Squamous Cell - virology
Cervical cancer
Cervix
Cervix Cancer Research Network (CCRN)
Chemoradiotherapy
Chemoradiotherapy, Adjuvant
Chemotherapy
Cisplatin
Cisplatin - therapeutic use
Developing countries
developing world
Early Detection of Cancer
Early Medical Intervention
Female
Fertility Preservation
Global Health
Gynecological Cancer InterGroup (GCIG)
Human papillomavirus
human papillomavirus (HPV)
Humans
Hysterectomy
Infections
LDCs
Malignancy
Neoplasms, Cystic, Mucinous, and Serous - pathology
Neoplasms, Cystic, Mucinous, and Serous - therapy
Oncology
Papillomavirus Infections - prevention & control
Papillomavirus Vaccines - therapeutic use
Prevention
Radiation therapy
Radiotherapy, Adjuvant
Surgery
Uterine Cervical Neoplasms - pathology
Uterine Cervical Neoplasms - prevention & control
Uterine Cervical Neoplasms - therapy
Uterine Cervical Neoplasms - virology
Vaccination
human papillomavirus (HPV)
developing world
Cervix Cancer Research Network (CCRN)
Gynecological Cancer InterGroup (GCIG)
brachytherapy
cervical cancer
chemotherapy
activism
vaccination
ISSN:0008-543X, 1097-0142, 1097-0142
Online Access:Get full text
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Summary:Cervical cancer is the fourth most common malignancy diagnosed in women worldwide. Nearly all cases of cervical cancer result from infection with the human papillomavirus, and the prevention of cervical cancer includes screening and vaccination. Primary treatment options for patients with cervical cancer may include surgery or a concurrent chemoradiotherapy regimen consisting of cisplatin‐based chemotherapy with external beam radiotherapy and brachytherapy. Cervical cancer causes more than one quarter of a million deaths per year as a result of grossly deficient treatments in many developing countries. This warrants a concerted global effort to counter the shocking loss of life and suffering that largely goes unreported. This article provides a review of the biology, prevention, and treatment of cervical cancer, and discusses the global cervical cancer crisis and efforts to improve the prevention and treatment of the disease in underdeveloped countries. Cancer 2017;123:2404–12. © 2017 American Cancer Society. Cervical cancer is a leading cause of death worldwide. In this article, the authors discuss the biology, prevention, and treatment of this disease, in addition to activist efforts aimed at improving treatment and access to care.
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ISSN:0008-543X
1097-0142
1097-0142
DOI:10.1002/cncr.30667