Flow cytometric osmotic fragility test and eosin‐5’‐maleimide dye‐binding tests are better than conventional osmotic fragility tests for the diagnosis of hereditary spherocytosis

Introduction Hereditary spherocytosis (HS) is the most common inherited hemolytic anemia with heterogeneous clinico‐laboratory manifestations. We evaluated the flow‐cytometric tests: eosin‐5’‐maleimide (EMA) and flow‐cytometric osmotic fragility test (FOFT) and the conventional osmotic fragility tes...

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Bibliographic Details
Published in:	International journal of laboratory hematology Vol. 40; no. 3; pp. 335 - 342
Main Authors:	Arora, R. D., Dass, J., Maydeo, S., Arya, V., Radhakrishnan, N., Sachdeva, A., Kotwal, J., Bhargava, M.
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01.06.2018
Subjects:	Adult Aged Anemia Diagnosis Dyes Eosine Yellowish-(YS) - analogs & derivatives Eosine Yellowish-(YS) - metabolism eosin‐5’‐maleimide eosin‐5’‐maleimide decrease Erythrocytes flow cytometric Flow cytometry Flow Cytometry - methods flow osmotic fragility tests Hereditary spherocytosis Humans Immune hemolytic anemia Middle Aged Osmotic Fragility residual red cells Sensitivity and Specificity Spherocytosis Spherocytosis, Hereditary - diagnosis eosin-5’-maleimide decrease eosin-5’-maleimide flow cytometric residual red cells flow osmotic fragility tests Hereditary spherocytosis
ISSN:	1751-5521, 1751-553X, 1751-553X
Online Access:	Get full text
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