Effects of Exercise on Patellar Cartilage in Women with Mild Knee Osteoarthritis

This study aims to investigate the effects of exercise on patellar cartilage using T2 relaxation time mapping of magnetic resonance imaging in postmenopausal women with mild patellofemoral joint osteoarthritis (OA). Eighty postmenopausal women (mean age, 58 (SD, 4.2) yr) with mild knee OA were rando...

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Vydané v:Medicine and science in sports and exercise Ročník 47; číslo 9; s. 1767
Hlavní autori: Koli, Jarmo, Multanen, Juhani, Kujala, Urho M, Häkkinen, Arja, Nieminen, Miika T, Kautiainen, Hannu, Lammentausta, Eveliina, Jämsä, Timo, Ahola, Riikka, Selänne, Harri, Kiviranta, Ilkka, Heinonen, Ari
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 01.09.2015
Predmet:
Aged
Biomechanical Phenomena
Cartilage, Articular - pathology
Cartilage, Articular - physiopathology
Exercise Therapy - adverse effects
Female
Humans
Magnetic Resonance Imaging
Middle Aged
Osteoarthritis, Knee - pathology
Osteoarthritis, Knee - physiopathology
Osteoarthritis, Knee - therapy
Patellofemoral Joint - pathology
Patellofemoral Joint - physiopathology
Physical Fitness
Postmenopause
Treatment Outcome
ISSN:1530-0315, 1530-0315
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Popis
Shrnutí:This study aims to investigate the effects of exercise on patellar cartilage using T2 relaxation time mapping of magnetic resonance imaging in postmenopausal women with mild patellofemoral joint osteoarthritis (OA). Eighty postmenopausal women (mean age, 58 (SD, 4.2) yr) with mild knee OA were randomized to either a supervised progressive impact exercise program three times a week for 12 months (n = 40) or a nonintervention control group (n = 40). Biochemical properties of cartilage were estimated using T2 relaxation time mapping, a parameter sensitive to collagen integrity, collagen orientation, and tissue hydration. Leg muscle strength and power, aerobic capacity, and self-rated assessment with the Knee Injury and Osteoarthritis Outcome Score were also measured. After intervention, full-thickness patellar cartilage T2 values had medium-size effect (d = 0.59; 95% confidence interval, 0.16 to 0.97; P = 0.018); the change difference was 7% greater in the exercise group compared with the control group. In the deep half of tissue, the significant exercise effect size was medium (d = 0.56; 95% confidence interval, 0.13 to 0.99; P = 0.013); the change difference was 8% greater in the exercise group compared with controls. Furthermore, significant medium-size T2 effects were found in the total lateral segment, lateral deep, and lateral superficial zones in favor of the exercise group. Extension force was 11% greater (d = 0.63, P = 0.006) and maximal aerobic capacity was 4% greater (d = 0.55, P = 0.028) in the exercise group than in controls. No changes in Knee Injury and Osteoarthritis Outcome Score emerged between the groups. Progressively implemented high-impact and intensive exercise creates enough stimuli and exerts favorable effects on patellar cartilage quality and physical function in postmenopausal women with mild knee OA.
Bibliografia:ObjectType-Article-1
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ISSN:1530-0315
1530-0315
DOI:10.1249/MSS.0000000000000629