Programming gene and engineered-cell therapies with synthetic biology

Gene and engineered-cell therapies promise to treat diseases by genetically modifying cells to carry out therapeutic tasks. Although the field has had some success in treating monogenic disorders and hematological malignancies, current approaches are limited to overexpression of one or a few transge...

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Bibliographic Details

Published in:	Science (American Association for the Advancement of Science) Vol. 359; no. 6376
Main Authors:	Kitada, Tasuku, DiAndreth, Breanna, Teague, Brian, Weiss, Ron
Format:	Journal Article
Language:	English
Published:	United States 09.02.2018
Subjects:	Cell Engineering - methods Cell- and Tissue-Based Therapy Cellular Reprogramming Techniques DNA - genetics Gene Expression Gene Regulatory Networks Genes, Synthetic Genetic Engineering - methods Genetic Therapy Humans Recombinant Fusion Proteins RNA - genetics Synthetic Biology - methods Transgenes
ISSN:	1095-9203, 1095-9203
Online Access:	Get more information
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