Convergent evolution and B-cell recirculation in germinal centers in a human lymph node

Germinal centers (GCs) play a central role in generating an effective immune response against infectious pathogens, and failures in their regulating mechanisms can lead to the development of autoimmune diseases and cancer. Although previous works study experimental systems of the immune response wit...

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Veröffentlicht in:	Life science alliance Jg. 6; H. 11; S. e202301959
Hauptverfasser:	Pelissier, Aurelien, Stratigopoulou, Maria, Donner, Naomi, Dimitriadis, Evangelos, Bende, Richard J, Guikema, Jeroen E, Rodriguez Martinez, Maria, van Noesel, Carel JM
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Life Science Alliance 01.11.2023 Life Science Alliance LLC
Schlagworte:	Animal models Animals Antigens Autoimmune Diseases B-Lymphocytes Cloning Competitive advantage Germinal Center Germinal centers Humans Immunization Lymph Nodes Lymphatic system Lymphocytes B Mice Mutation Phylogeny Reproducibility
ISSN:	2575-1077, 2575-1077
Online-Zugang:	Volltext
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