A guide to immunotherapy for COVID-19

Immune dysregulation is an important component of the pathophysiology of COVID-19. A large body of literature has reported the effect of immune-based therapies in patients with COVID-19, with some remarkable successes such as the use of steroids or anti-cytokine therapies. However, challenges in cli...

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Bibliographic Details
Published in:	Nature medicine Vol. 28; no. 1; pp. 39 - 50
Main Authors:	van de Veerdonk, Frank L., Giamarellos-Bourboulis, Evangelos, Pickkers, Peter, Derde, Lennie, Leavis, Helen, van Crevel, Reinout, Engel, Job J., Wiersinga, W. Joost, Vlaar, Alexander P. J., Shankar-Hari, Manu, van der Poll, Tom, Bonten, Marc, Angus, Derek C., van der Meer, Jos W. M., Netea, Mihai G.
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01.01.2022 Nature Publishing Group
Subjects:	631/250 631/250/251 Algorithms Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Humanized - therapeutic use Antibodies, Neutralizing - therapeutic use Anticoagulants - therapeutic use Azetidines - therapeutic use Biomedical and Life Sciences Biomedicine Bradykinin - analogs & derivatives Bradykinin - therapeutic use Bradykinin B2 Receptor Antagonists - therapeutic use Cancer Research Clinical decision making Clinical trials Complement Inactivating Agents - therapeutic use Coronaviruses COVID-19 COVID-19 - immunology COVID-19 - therapy Cytokines Decision making Dexamethasone - therapeutic use Drug Combinations Factor Xa Inhibitors - therapeutic use Glucocorticoids - therapeutic use Heparin - therapeutic use Heterogeneity Humans Hydrocortisone - therapeutic use Imatinib Mesylate - therapeutic use Immunization, Passive Immunologic Factors - therapeutic use Immunomodulation Immunotherapy Infectious Diseases Interferon beta-1a - therapeutic use Interferon beta-1b - therapeutic use Interferon-gamma - therapeutic use Interleukin 1 Receptor Antagonist Protein - therapeutic use Kallikrein-Kinin System Metabolic Diseases Molecular Medicine Neurosciences Patients Phenotypes Piperidines - therapeutic use Protein Kinase Inhibitors - therapeutic use Purines - therapeutic use Pyrazoles - therapeutic use Pyrimidines - therapeutic use Review Article SARS-CoV-2 Steroid hormones Sulfonamides - therapeutic use
ISSN:	1078-8956, 1546-170X, 1546-170X
Online Access:	Get full text
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