Shanghai Time Outside to Reduce Myopia trial: design and baseline data

Importance Myopia is a major public health concern worldwide, while outdoor time is indicated to be protective against the onset of myopia. Background To describe the methodology and baseline data of the Shanghai Time Outside to Reduce Myopia (STORM) trial. Design A 2‐year, school‐based, prospective...

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Veröffentlicht in:Clinical & experimental ophthalmology Jg. 47; H. 2; S. 171 - 178
Hauptverfasser: He, Xiangui, Sankaridurg, Padmaja, Xiong, Shuyu, Li, Wayne, Zhang, Bo, Weng, Rebecca, Zhu, Jianfeng, Naduvilath, Thomas, Resnikoff, Serge, Zou, Haidong, Xu, Xun
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Sprache:Englisch
Veröffentlicht: Melbourne John Wiley & Sons Australia, Ltd 01.03.2019
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ISSN:1442-6404, 1442-9071, 1442-9071
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Abstract Importance Myopia is a major public health concern worldwide, while outdoor time is indicated to be protective against the onset of myopia. Background To describe the methodology and baseline data of the Shanghai Time Outside to Reduce Myopia (STORM) trial. Design A 2‐year, school‐based, prospective, cluster randomized trial. Participants Children from grade I and II classes of 24 schools from eight districts in Shanghai, China, were randomized to either a control group, a test group I (40‐min outdoor time/day) or test group II (80‐min outdoor time/day). Methods At baseline and annual intervals, cycloplegic autorefraction and axial length measurement will be performed. Time outdoors and light exposure will be monitored via parent/carer questionnaires and a wearable device. Main Outcome Measures Spherical equivalent, prevalence of myopia and time outdoors in each group. Results A total of 6295 eligible children (age 7.2 ± 0.7 y [6‐9 y]) were randomized to control (n = 2037), test group I (n = 2329) and test group II (n = 1929). At baseline, spherical equivalent was +0.98 ± 1.02D, +1.02 ± 1.02D and +1.00 ± 0.99D (P = 0.708), myopia prevalence was 8.9, 7.7 and 7.8% (P = 0.270) and time outdoors was 58.5 ± 35.8, 59.8 ± 34.7 and 58.5 ± 35.3 min/d (P = 0.886) for control, test groups I and II, respectively. Conclusions and Relevance Myopia prevalence was high at nearly 8 to 9% in school children aged 7 years in Shanghai, China. The current trial will help evaluate if increased time outdoors has a role to play in reducing the incidence of myopia and/or slow the progression of myopia.
AbstractList Importance Myopia is a major public health concern worldwide, while outdoor time is indicated to be protective against the onset of myopia. Background To describe the methodology and baseline data of the Shanghai Time Outside to Reduce Myopia (STORM) trial. Design A 2‐year, school‐based, prospective, cluster randomized trial. Participants Children from grade I and II classes of 24 schools from eight districts in Shanghai, China, were randomized to either a control group, a test group I (40‐min outdoor time/day) or test group II (80‐min outdoor time/day). Methods At baseline and annual intervals, cycloplegic autorefraction and axial length measurement will be performed. Time outdoors and light exposure will be monitored via parent/carer questionnaires and a wearable device. Main Outcome Measures Spherical equivalent, prevalence of myopia and time outdoors in each group. Results A total of 6295 eligible children (age 7.2 ± 0.7 y [6‐9 y]) were randomized to control (n = 2037), test group I (n = 2329) and test group II (n = 1929). At baseline, spherical equivalent was +0.98 ± 1.02D, +1.02 ± 1.02D and +1.00 ± 0.99D (P = 0.708), myopia prevalence was 8.9, 7.7 and 7.8% (P = 0.270) and time outdoors was 58.5 ± 35.8, 59.8 ± 34.7 and 58.5 ± 35.3 min/d (P = 0.886) for control, test groups I and II, respectively. Conclusions and Relevance Myopia prevalence was high at nearly 8 to 9% in school children aged 7 years in Shanghai, China. The current trial will help evaluate if increased time outdoors has a role to play in reducing the incidence of myopia and/or slow the progression of myopia.
Myopia is a major public health concern worldwide, while outdoor time is indicated to be protective against the onset of myopia. To describe the methodology and baseline data of the Shanghai Time Outside to Reduce Myopia (STORM) trial. A 2-year, school-based, prospective, cluster randomized trial. Children from grade I and II classes of 24 schools from eight districts in Shanghai, China, were randomized to either a control group, a test group I (40-min outdoor time/day) or test group II (80-min outdoor time/day). At baseline and annual intervals, cycloplegic autorefraction and axial length measurement will be performed. Time outdoors and light exposure will be monitored via parent/carer questionnaires and a wearable device. Spherical equivalent, prevalence of myopia and time outdoors in each group. A total of 6295 eligible children (age 7.2 ± 0.7 y [6-9 y]) were randomized to control (n = 2037), test group I (n = 2329) and test group II (n = 1929). At baseline, spherical equivalent was +0.98 ± 1.02D, +1.02 ± 1.02D and +1.00 ± 0.99D (P = 0.708), myopia prevalence was 8.9, 7.7 and 7.8% (P = 0.270) and time outdoors was 58.5 ± 35.8, 59.8 ± 34.7 and 58.5 ± 35.3 min/d (P = 0.886) for control, test groups I and II, respectively. Myopia prevalence was high at nearly 8 to 9% in school children aged 7 years in Shanghai, China. The current trial will help evaluate if increased time outdoors has a role to play in reducing the incidence of myopia and/or slow the progression of myopia.
Myopia is a major public health concern worldwide, while outdoor time is indicated to be protective against the onset of myopia.IMPORTANCEMyopia is a major public health concern worldwide, while outdoor time is indicated to be protective against the onset of myopia.To describe the methodology and baseline data of the Shanghai Time Outside to Reduce Myopia (STORM) trial.BACKGROUNDTo describe the methodology and baseline data of the Shanghai Time Outside to Reduce Myopia (STORM) trial.A 2-year, school-based, prospective, cluster randomized trial.DESIGNA 2-year, school-based, prospective, cluster randomized trial.Children from grade I and II classes of 24 schools from eight districts in Shanghai, China, were randomized to either a control group, a test group I (40-min outdoor time/day) or test group II (80-min outdoor time/day).PARTICIPANTSChildren from grade I and II classes of 24 schools from eight districts in Shanghai, China, were randomized to either a control group, a test group I (40-min outdoor time/day) or test group II (80-min outdoor time/day).At baseline and annual intervals, cycloplegic autorefraction and axial length measurement will be performed. Time outdoors and light exposure will be monitored via parent/carer questionnaires and a wearable device.METHODSAt baseline and annual intervals, cycloplegic autorefraction and axial length measurement will be performed. Time outdoors and light exposure will be monitored via parent/carer questionnaires and a wearable device.Spherical equivalent, prevalence of myopia and time outdoors in each group.MAIN OUTCOME MEASURESSpherical equivalent, prevalence of myopia and time outdoors in each group.A total of 6295 eligible children (age 7.2 ± 0.7 y [6-9 y]) were randomized to control (n = 2037), test group I (n = 2329) and test group II (n = 1929). At baseline, spherical equivalent was +0.98 ± 1.02D, +1.02 ± 1.02D and +1.00 ± 0.99D (P = 0.708), myopia prevalence was 8.9, 7.7 and 7.8% (P = 0.270) and time outdoors was 58.5 ± 35.8, 59.8 ± 34.7 and 58.5 ± 35.3 min/d (P = 0.886) for control, test groups I and II, respectively.RESULTSA total of 6295 eligible children (age 7.2 ± 0.7 y [6-9 y]) were randomized to control (n = 2037), test group I (n = 2329) and test group II (n = 1929). At baseline, spherical equivalent was +0.98 ± 1.02D, +1.02 ± 1.02D and +1.00 ± 0.99D (P = 0.708), myopia prevalence was 8.9, 7.7 and 7.8% (P = 0.270) and time outdoors was 58.5 ± 35.8, 59.8 ± 34.7 and 58.5 ± 35.3 min/d (P = 0.886) for control, test groups I and II, respectively.Myopia prevalence was high at nearly 8 to 9% in school children aged 7 years in Shanghai, China. The current trial will help evaluate if increased time outdoors has a role to play in reducing the incidence of myopia and/or slow the progression of myopia.CONCLUSIONS AND RELEVANCEMyopia prevalence was high at nearly 8 to 9% in school children aged 7 years in Shanghai, China. The current trial will help evaluate if increased time outdoors has a role to play in reducing the incidence of myopia and/or slow the progression of myopia.
ImportanceMyopia is a major public health concern worldwide, while outdoor time is indicated to be protective against the onset of myopia.BackgroundTo describe the methodology and baseline data of the Shanghai Time Outside to Reduce Myopia (STORM) trial.DesignA 2‐year, school‐based, prospective, cluster randomized trial.ParticipantsChildren from grade I and II classes of 24 schools from eight districts in Shanghai, China, were randomized to either a control group, a test group I (40‐min outdoor time/day) or test group II (80‐min outdoor time/day).MethodsAt baseline and annual intervals, cycloplegic autorefraction and axial length measurement will be performed. Time outdoors and light exposure will be monitored via parent/carer questionnaires and a wearable device.Main Outcome MeasuresSpherical equivalent, prevalence of myopia and time outdoors in each group.ResultsA total of 6295 eligible children (age 7.2 ± 0.7 y [6‐9 y]) were randomized to control (n = 2037), test group I (n = 2329) and test group II (n = 1929). At baseline, spherical equivalent was +0.98 ± 1.02D, +1.02 ± 1.02D and +1.00 ± 0.99D (P = 0.708), myopia prevalence was 8.9, 7.7 and 7.8% (P = 0.270) and time outdoors was 58.5 ± 35.8, 59.8 ± 34.7 and 58.5 ± 35.3 min/d (P = 0.886) for control, test groups I and II, respectively.Conclusions and RelevanceMyopia prevalence was high at nearly 8 to 9% in school children aged 7 years in Shanghai, China. The current trial will help evaluate if increased time outdoors has a role to play in reducing the incidence of myopia and/or slow the progression of myopia.
Author Naduvilath, Thomas
Li, Wayne
Weng, Rebecca
Zou, Haidong
Resnikoff, Serge
Sankaridurg, Padmaja
Xiong, Shuyu
Zhang, Bo
Xu, Xun
Zhu, Jianfeng
He, Xiangui
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  surname: He
  fullname: He, Xiangui
  organization: Fudan University
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  surname: Sankaridurg
  fullname: Sankaridurg, Padmaja
  organization: University of New South Wales, Sydney
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  givenname: Shuyu
  surname: Xiong
  fullname: Xiong, Shuyu
  organization: Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai Key Laboratory of Ocular Fundus Diseases
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  givenname: Wayne
  surname: Li
  fullname: Li, Wayne
  organization: Brien Holden Vision Institute
– sequence: 5
  givenname: Bo
  surname: Zhang
  fullname: Zhang, Bo
  organization: Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital
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  givenname: Rebecca
  surname: Weng
  fullname: Weng, Rebecca
  organization: Brien Holden Vision Institute
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  surname: Zhu
  fullname: Zhu, Jianfeng
  organization: Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital
– sequence: 8
  givenname: Thomas
  surname: Naduvilath
  fullname: Naduvilath, Thomas
  organization: Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai Key Laboratory of Ocular Fundus Diseases
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  givenname: Serge
  surname: Resnikoff
  fullname: Resnikoff, Serge
  organization: Brien Holden Vision Institute
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  givenname: Haidong
  surname: Zou
  fullname: Zou, Haidong
  organization: Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai Key Laboratory of Ocular Fundus Diseases
– sequence: 11
  givenname: Xun
  orcidid: 0000-0002-4246-4343
  surname: Xu
  fullname: Xu, Xun
  email: drxuxun@sjtu.edu.cn
  organization: Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai Key Laboratory of Ocular Fundus Diseases
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30207041$$D View this record in MEDLINE/PubMed
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myopia
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Snippet Importance Myopia is a major public health concern worldwide, while outdoor time is indicated to be protective against the onset of myopia. Background To...
Myopia is a major public health concern worldwide, while outdoor time is indicated to be protective against the onset of myopia. To describe the methodology...
ImportanceMyopia is a major public health concern worldwide, while outdoor time is indicated to be protective against the onset of myopia.BackgroundTo describe...
Myopia is a major public health concern worldwide, while outdoor time is indicated to be protective against the onset of myopia.IMPORTANCEMyopia is a major...
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StartPage 171
SubjectTerms Child
Children
China - epidemiology
Cluster Analysis
Female
Humans
Incidence
intervention
Male
Myopia
Myopia - epidemiology
Myopia - prevention & control
Ophthalmology
outdoor
Outdoors
Prevalence
prevention
Prospective Studies
Public health
Recreation - physiology
Refraction, Ocular
Research Design
Schools
Surveys and Questionnaires
Title Shanghai Time Outside to Reduce Myopia trial: design and baseline data
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fceo.13391
https://www.ncbi.nlm.nih.gov/pubmed/30207041
https://www.proquest.com/docview/2194010377
https://www.proquest.com/docview/2102921092
Volume 47
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