Correlation of serpin–protease expression by comparative analysis of real-time PCR profiling data

Imbalanced protease activity has long been recognized in the progression of disease states such as cancer and inflammation. Serpins, the largest family of endogenous protease inhibitors, target a wide variety of serine and cysteine proteases and play a role in a number of physiological and pathologi...

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Bibliographic Details
Published in:	Genomics (San Diego, Calif.) Vol. 88; no. 2; pp. 173 - 184
Main Authors:	Badola, Sunita, Spurling, Heidi, Robison, Keith, Fedyk, Eric R., Silverman, Gary A., Strayle, Jochen, Kapeller, Rosana, Tsu, Christopher A.
Format:	Journal Article
Language:	English
Published:	San Diego, CA Elsevier Inc 01.08.2006 Elsevier
Subjects:	Amino Acid Sequence Biological and medical sciences Cancer Cell Line Cell Line, Transformed Cysteine Endopeptidases - genetics Cysteine Endopeptidases - metabolism Disease Progression Expression profiling Female Fundamental and applied biological sciences. Psychology Gene correlation Gene Expression Profiling - methods Gene Expression Regulation Gene Expression Regulation, Enzymologic Genes. Genome Genetics of eukaryotes. Biological and molecular evolution Humans Imbalance Male Molecular and cellular biology Molecular genetics Molecular Sequence Data Neoplasms - genetics Neoplasms - metabolism PCR Polymerase Chain Reaction - methods Protease Serine Endopeptidases - genetics Serine Endopeptidases - metabolism Serpin Serpins - genetics Serpins - metabolism Species Specificity CHF Expression profiling UUI SMC RSL IBD siRNA PBMC BM-MNC Imbalance Protease serpin DRG Gene correlation BPH B2M PCR COPD Cancer Correlation Enzyme Genomics Time Malignant tumor Gene expression Polymerase chain reaction Peptidases Serpin Gene Analysis Hydrolases
ISSN:	0888-7543, 1089-8646
Online Access:	Get full text
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