Rational approach in the management of Pseudomonas aeruginosa infections
This review details the management of Pseudomonas aeruginosa infections covering both current and future treatment options that are and may be available for the clinicians. Pseudomonas aeruginosa infections are a great concern in hospital-acquired infections with very limited therapeutic options. Th...
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| Vydané v: | Current opinion in infectious diseases Ročník 31; číslo 6; s. 578 |
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| Hlavní autori: | , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
United States
01.12.2018
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| ISSN: | 1473-6527, 1473-6527 |
| On-line prístup: | Zistit podrobnosti o prístupe |
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| Shrnutí: | This review details the management of Pseudomonas aeruginosa infections covering both current and future treatment options that are and may be available for the clinicians.
Pseudomonas aeruginosa infections are a great concern in hospital-acquired infections with very limited therapeutic options. The increasing antibiotic resistance has led to a need for different treatment choices that range from the use of new antibiotics to new nonantibiotic alternative agents to kill or disarm the pathogen.
New molecules such as ceftolozane-tazobactam, ceftazidime-avibactam, and imipenem-relebactam have shown an adequate activity against P. aeruginosa, especially against multidrug resistance strains. Other nonantibiotic alternative treatments, such as antibodies, bacteriocins or phage therapy, have shown promising results, but future clinical studies are needed. |
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| Bibliografia: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 |
| ISSN: | 1473-6527 1473-6527 |
| DOI: | 10.1097/QCO.0000000000000505 |