Doxorubicin-Loaded Magnetic Silk Fibroin Nanoparticles for Targeted Therapy of Multidrug-Resistant Cancer

A strategy to prepare doxorubicin‐loaded magnetic silk fibroin nanoparticles is presented. The nanoparticles serve as a nanometer‐scale drug‐delivery system in the chemotherapy of multidrug‐resistant cancer under the guidance of a magnetic field. The magnetic tumor‐targeting ability broadens the ran...

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Veröffentlicht in:	Advanced materials (Weinheim) Jg. 26; H. 43; S. 7393 - 7398
Hauptverfasser:	Tian, Ye, Jiang, Xuejiao, Chen, Xin, Shao, Zhengzhong, Yang, Wuli
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Germany Blackwell Publishing Ltd 19.11.2014
Schlagworte:	Animals Antineoplastic Agents - administration & dosage Biomedical materials Bombyx Cancer Cell Line, Tumor Cell Survival - drug effects Doxorubicin - chemistry drug delivery Drug Delivery Systems - methods Drug Resistance, Neoplasm Female Ferric Compounds - chemistry Fibroins - chemistry Humans Hydrogen-Ion Concentration Hydrophobic and Hydrophilic Interactions Magnetic Fields magnetic guidance Magnets - chemistry Mice, Inbred BALB C Mice, Nude Nanoparticles Nanoparticles - chemistry Nanostructure Neoplasm Transplantation Silk fibroin Static Electricity Strategy Therapy magnetic guidance nanoparticles drug delivery silk fibroin
ISSN:	0935-9648, 1521-4095, 1521-4095
Online-Zugang:	Volltext
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