Chromothripsis in hematologic malignancies
•Chromothripsis occurs when chromosomes shatter and reassemble randomly.•Chromothripsis can activate oncogenes, form fusion genes, or cause loss of tumor suppressors.•Chromothripsis occurs in several hematologic malignancies and is associated with loss of TP53 in these malignancies.•Chromothripsis i...
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| Published in: | Experimental hematology Vol. 132; p. 104172 |
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| Main Author: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
Netherlands
Elsevier Inc
01.04.2024
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| ISSN: | 0301-472X, 1873-2399, 1873-2399 |
| Online Access: | Get full text |
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