Is aging a barrier to reprogramming? Lessons from induced pluripotent stem cells

The discovery of induced pluripotent stem cells (iPSCs) has the potential to revolutionize the field of regenerative medicine. In the past few years, iPSCs have been the subject of intensive research towards their application in disease modeling and drug screening. In the future, these cells may be...

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Vydáno v:	Biogerontology (Dordrecht) Ročník 14; číslo 6; s. 591 - 602
Hlavní autoři:	Phanthong, Phetcharat, Raveh-Amit, Hadas, Li, Tong, Kitiyanant, Yindee, Dinnyes, Andras
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Dordrecht Springer Netherlands 01.12.2013 Springer Nature B.V
Témata:	Age Factors Aging Aging - genetics Aging - metabolism Aging - pathology Aging, Premature - genetics Aging, Premature - metabolism Aging, Premature - pathology Aging, Premature - physiopathology Aging, Premature - therapy Anatomical systems Animals Biomedical and Life Sciences Cell Biology Cellular Reprogramming Cellular Senescence Deoxyribonucleic acid Developmental Biology DNA Gene Expression Regulation, Developmental Genetic Therapy - methods Genomes Genomics Geriatrics/Gerontology Humans Induced Pluripotent Stem Cells - metabolism Induced Pluripotent Stem Cells - pathology Life Sciences Medical screening Medicine Nuclear Transfer Techniques Regenerative medicine Regenerative Medicine - methods Research applications Review Article Senescence Stem cells Telomerase Tumors Hungary Thailand Aging Premature aging Nuclear reprogramming Induced pluripotent stem cells Cellular senescence
ISSN:	1389-5729, 1573-6768, 1573-6768
On-line přístup:	Získat plný text
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