Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

Dendritic cells (DCs) have the capacity to initiate immune responses, but it has been postulated that they may also be involved in inducing peripheral tolerance. To examine the function of DCs in the steady state we devised an antigen delivery system targeting these specialized antigen presenting ce...

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Bibliographic Details
Published in:	The Journal of experimental medicine Vol. 194; no. 6; p. 769
Main Authors:	Hawiger, D, Inaba, K, Dorsett, Y, Guo, M, Mahnke, K, Rivera, M, Ravetch, J V, Steinman, R M, Nussenzweig, M C
Format:	Journal Article
Language:	English
Published:	United States 17.09.2001
Subjects:	Animals Antigen Presentation - immunology Antigens, CD - immunology B7-2 Antigen CD40 Antigens - immunology Dendritic Cells - immunology Female Lectins, C-Type Lymphocyte Activation - immunology Lymphocytes - immunology Membrane Glycoproteins - immunology Mice Mice, Inbred C57BL Minor Histocompatibility Antigens Muramidase - immunology Receptors, Cell Surface - immunology Spleen - cytology T-Lymphocytes - immunology
ISSN:	0022-1007
Online Access:	Get more information
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