An effective polyvinyl alcohol for the solubilization of poorly water-soluble drugs in solid dispersion formulations

This study aimed to investigate the characteristics of an effective polyvinyl alcohol (PVA) for use in solid dispersion formulations (SDFs), which enable higher dissolution and bioavailability of poorly water-soluble drugs. PVAs with different degrees of hydrolysis and polymerization were evaluated...

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Veröffentlicht in:	Journal of drug delivery science and technology Jg. 55; S. 101401
Hauptverfasser:	Umemoto, Yoshiaki, Uchida, Shinya, Yoshida, Takatsune, Shimada, Ken, Kojima, Hiroyuki, Takagi, Akira, Tanaka, Shimako, Kashiwagura, Yasuharu, Namiki, Noriyuki
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Elsevier B.V 01.02.2020
Schlagworte:	Amenamevir Nifedipine Polyvinyl alcohol Rat Solid dispersion Tacrolimus Solid dispersion Amenamevir Polyvinyl alcohol Tacrolimus Rat Nifedipine
ISSN:	1773-2247
Online-Zugang:	Volltext
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