Decoding complexity in biomolecular recognition of DNA i-motifs with microarrays

Abstract DNA i-motifs (iMs) are non-canonical C-rich secondary structures implicated in numerous cellular processes. Though iMs exist throughout the genome, our understanding of iM recognition by proteins or small molecules is limited to a few examples. We designed a DNA microarray containing 10976...

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Veröffentlicht in:	Nucleic acids research Jg. 51; H. 22; S. 12020 - 12030
Hauptverfasser:	Yazdani, Kamyar, Seshadri, Srinath, Tillo, Desiree, Yang, Mo, Sibley, Christopher D, Vinson, Charles, Schneekloth, John S
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Oxford University Press 11.12.2023
Schlagworte:	Chemical Biology and Nucleic Acid Chemistry DNA - chemistry G-Quadruplexes Heterogeneous-Nuclear Ribonucleoprotein K Humans Mitoxantrone Nucleotide Motifs Oligonucleotide Array Sequence Analysis
ISSN:	0305-1048, 1362-4962, 1362-4962
Online-Zugang:	Volltext
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