Optimization of the split-spectrum amplitude-decorrelation angiography algorithm on a spectral optical coherence tomography system

The split-spectrum amplitude-decorrelation angiography algorithm was optimized on a spectral optical coherence tomography system using a flow phantom. The number of times the spectrum was split and the bandwidth of each split were adjusted to maximize the flow phantom decorrelation signal-to-noise r...

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Vydáno v:Optics letters Ročník 40; číslo 10; s. 2305
Hlavní autoři: Gao, Simon S, Liu, Gangjun, Huang, David, Jia, Yali
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 15.05.2015
Témata:
Adult
Algorithms
Angiography
Humans
Image Processing, Computer-Assisted - methods
Phantoms, Imaging
Retina - diagnostic imaging
Signal-To-Noise Ratio
Tomography, Optical Coherence
ISSN:1539-4794, 1539-4794
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Shrnutí:The split-spectrum amplitude-decorrelation angiography algorithm was optimized on a spectral optical coherence tomography system using a flow phantom. The number of times the spectrum was split and the bandwidth of each split were adjusted to maximize the flow phantom decorrelation signal-to-noise ratio. The improvement in flow detection was then demonstrated with en face retinal angiograms. The optimized algorithm increased the detectable retinal microvascular flow and decreased the variability of the quantified vessel density in OCT retinal angiograms of healthy human subjects.
Bibliografie:ObjectType-Article-1
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ISSN:1539-4794
1539-4794
DOI:10.1364/OL.40.002305