Cryo-EM structure of the Smc5/6 holo-complex

Abstract The Smc5/6 complex plays an essential role in the resolution of recombination intermediates formed during mitosis or meiosis, or as a result of the cellular response to replication stress. It also functions as a restriction factor preventing viral replication. Here, we report the cryogenic...

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Bibliographic Details

Published in:	Nucleic acids research Vol. 50; no. 16; pp. 9505 - 9520
Main Authors:	Hallett, Stephen T, Campbell Harry, Isabella, Schellenberger, Pascale, Zhou, Lihong, Cronin, Nora B, Baxter, Jonathan, Etheridge, Thomas J, Murray, Johanne M, Oliver, Antony W
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 09.09.2022
Subjects:	Cell Cycle Proteins - metabolism Chromosomal Proteins, Non-Histone - genetics Chromosomal Proteins, Non-Histone - metabolism Cryoelectron Microscopy Nuclear Proteins - metabolism Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - metabolism Structural Biology
ISSN:	0305-1048, 1362-4962, 1362-4962
Online Access:	Get full text
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