Accurate detection of outliers and subpopulations with Pmetrics, a nonparametric and parametric pharmacometric modeling and simulation package for R

Nonparametric population modeling algorithms have a theoretical superiority over parametric methods to detect pharmacokinetic and pharmacodynamic subgroups and outliers within a study population. The authors created "Pmetrics," a new Windows and Unix R software package that updates the old...

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Vydané v:	Therapeutic drug monitoring Ročník 34; číslo 4; s. 467
Hlavní autori:	Neely, Michael N, van Guilder, Michael G, Yamada, Walter M, Schumitzky, Alan, Jelliffe, Roger W
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.08.2012
Predmet:	Algorithms Bayes Theorem Drug Monitoring - methods Models, Biological Pharmacokinetics Software
ISSN:	1536-3694, 1536-3694
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