Reconstructing Complex Cancer Evolutionary Histories from Multiple Bulk DNA Samples Using Pairtree

Cancers are composed of genetically distinct subpopulations of malignant cells. DNA-sequencing data can be used to determine the somatic point mutations specific to each population and build clone trees describing the evolutionary relationships between them. These clone trees can reveal critical poi...

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Vydané v:	Blood cancer discovery Ročník 3; číslo 3; s. 208
Hlavní autori:	Wintersinger, Jeff A, Dobson, Stephanie M, Kulman, Ethan, Stein, Lincoln D, Dick, John E, Morris, Quaid
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 05.05.2022
Predmet:	Algorithms DNA Evolution, Molecular Humans Neoplasms - diagnosis Sequence Analysis, DNA
ISSN:	2643-3249, 2643-3249
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