Reconstructing Complex Cancer Evolutionary Histories from Multiple Bulk DNA Samples Using Pairtree

Cancers are composed of genetically distinct subpopulations of malignant cells. DNA-sequencing data can be used to determine the somatic point mutations specific to each population and build clone trees describing the evolutionary relationships between them. These clone trees can reveal critical poi...

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Bibliographic Details

Published in:	Blood cancer discovery Vol. 3; no. 3; p. 208
Main Authors:	Wintersinger, Jeff A, Dobson, Stephanie M, Kulman, Ethan, Stein, Lincoln D, Dick, John E, Morris, Quaid
Format:	Journal Article
Language:	English
Published:	United States 05.05.2022
Subjects:	Algorithms DNA Evolution, Molecular Humans Neoplasms - diagnosis Sequence Analysis, DNA
ISSN:	2643-3249, 2643-3249
Online Access:	Get more information
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