Primary Sclerosing Cholangitis and Inflammatory Bowel Disease

Primary sclerosing cholangitis (PSC) is a rare pathology seen in patients with inflammatory bowel disease (IBD), especially ulcerative colitis. PSC increases patients' morbidity and requires the attention of a multidisciplinary team as those patients require frequent colonoscopies and biopsies...

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Bibliographic Details
Published in:The Surgical clinics of North America Vol. 105; no. 2; p. 375
Main Authors: Escobar, Jessica Colin, Pereyra, Maria Navarez, Abbass, Mohammad Ali
Format: Journal Article
Language:English
Published: United States 01.04.2025
Subjects:
Cholangitis, Sclerosing - complications
Cholangitis, Sclerosing - diagnosis
Cholangitis, Sclerosing - etiology
Cholangitis, Sclerosing - therapy
Colitis, Ulcerative - complications
Humans
Inflammatory Bowel Diseases - complications
Inflammatory Bowel Diseases - diagnosis
Inflammatory Bowel Diseases - therapy
Progressive
Inflammatory
Surveillance
Cancer
Transplant
ISSN:1558-3171, 1558-3171
Online Access:Get more information
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Summary:Primary sclerosing cholangitis (PSC) is a rare pathology seen in patients with inflammatory bowel disease (IBD), especially ulcerative colitis. PSC increases patients' morbidity and requires the attention of a multidisciplinary team as those patients require frequent colonoscopies and biopsies due to the elevated risk of malignancy, biliary screening and management of progressive disease that could leave patients in liver failure requiring liver transplant. Some consider this a separate form of IBD in addition to Crohn's and ulcerative colitis. These patients should be monitored closely and managed carefully due to implications of ongoing management on quality of life and survival.
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ISSN:1558-3171
1558-3171
DOI:10.1016/j.suc.2024.11.001