Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1

Human immunodeficiency virus type 1 (HIV-1) vaccine development requires selection of appropriate envelope (Env) immunogens. Twenty HIV-1 Env glycoproteins were examined for their ability to bind human anti-HIV-1 monoclonal antibodies (MAbs) and then used as immunogens in guinea pigs to identify pro...

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Veröffentlicht in:	Journal of virology Jg. 87; H. 8; S. 4185
Hauptverfasser:	Liao, Hua-Xin, Tsao, Chun-Yen, Alam, S Munir, Muldoon, Mark, Vandergrift, Nathan, Ma, Ben-Jiang, Lu, Xiaozhi, Sutherland, Laura L, Scearce, Richard M, Bowman, Cindy, Parks, Robert, Chen, Haiyan, Blinn, Julie H, Lapedes, Alan, Watson, Sydeaka, Xia, Shi-Mao, Foulger, Andrew, Hahn, Beatrice H, Shaw, George M, Swanstrom, Ron, Montefiori, David C, Gao, Feng, Haynes, Barton F, Korber, Bette
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.04.2013
Schlagworte:	Animals Antibodies, Neutralizing - blood Antibody Affinity Antigens, Viral - genetics Antigens, Viral - immunology Cross Reactions env Gene Products, Human Immunodeficiency Virus - genetics env Gene Products, Human Immunodeficiency Virus - immunology Glycoproteins - genetics Glycoproteins - immunology Guinea Pigs HIV Antibodies - blood HIV-1 - genetics HIV-1 - immunology HIV-1 - isolation & purification Humans
ISSN:	1098-5514, 1098-5514
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