Histone deacetylase 1 plays a predominant pro-oncogenic role in Eμ-myc driven B cell lymphoma

The two histone deacetylases (Hdacs), Hdac1 and Hdac2, are erasers of acetylation marks on histone tails, and are important regulators of gene expression that were shown to play important roles in hematological malignancies. However, several recent studies reported opposing tumor-suppressive or tumo...

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Vydané v:	Scientific reports Ročník 6; číslo 1; s. 37772
Hlavní autori:	Pillonel, Vincent, Reichert, Nina, Cao, Chun, Heideman, Marinus R., Yamaguchi, Teppei, Matthias, Gabriele, Tzankov, Alexandar, Matthias, Patrick
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London Nature Publishing Group UK 25.11.2016 Nature Publishing Group
Predmet:	13 13/1 13/2 13/31 13/51 14/63 38/77 45/29 45/41 45/90 631/67/1990/291/1621/1915 631/80/458/1275 64/60 Animals Genes, myc Histone Deacetylase 1 - metabolism Histone Deacetylase 2 - metabolism Humanities and Social Sciences Humans Lymphoma, B-Cell - genetics Mice multidisciplinary Oncogenes Science
ISSN:	2045-2322, 2045-2322
On-line prístup:	Získať plný text
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