Nanoparticle brain delivery: a guide to verification methods

Many reports conclude nanoparticle (NP) brain entry based on bulk brain analysis. Bulk brain includes blood, cerebrospinal fluid and blood vessels within the brain contributing to the blood–brain and blood–cerebrospinal fluid barriers. Considering the brain as neurons, glia and their extracellular s...

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Bibliographic Details
Published in:	Nanomedicine (London, England) Vol. 15; no. 4; pp. 409 - 432
Main Author:	Yokel, Robert A
Format:	Journal Article
Language:	English
Published:	England Future Medicine Ltd 01.02.2020
Subjects:	Alzheimer's disease Antiretroviral drugs Blood Blood-brain barrier blood–cerebrospinal fluid barrier Brain brain parenchyma brain perfusion capillary depletion convection-enhanced delivery microdialysis Microscopy mouse nanoparticle Nanoparticles rat Research methodology mouse blood–brain barrier convection-enhanced delivery microdialysis rat blood–cerebrospinal fluid barrier nanoparticle brain parenchyma capillary depletion in situ brain perfusion
ISSN:	1743-5889, 1748-6963, 1748-6963
Online Access:	Get full text
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