Uterine natural killer cells initiate spiral artery remodeling in human pregnancy

Uterine spiral artery remodeling is required for successful human pregnancy; impaired remodeling is associated with pregnancy complications, including late miscarriage, preeclampsia, and fetal growth restriction. The molecular triggers of remodeling are not known, but it is now clear that there are...

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Vydané v:	The FASEB journal Ročník 26; číslo 12; s. 4876
Hlavní autori:	Robson, Andrew, Harris, Lynda K, Innes, Barbara A, Lash, Gendie E, Aljunaidy, Mais M, Aplin, John D, Baker, Philip N, Robson, Stephen C, Bulmer, Judith N
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.12.2012
Predmet:	Angiopoietin-1 - metabolism Angiopoietin-1 - pharmacology Angiopoietin-2 - metabolism Angiopoietin-2 - pharmacology Cell Line Cells, Cultured Culture Media, Conditioned - metabolism Culture Media, Conditioned - pharmacology Decidua - cytology Decidua - metabolism Extracellular Matrix - drug effects Extracellular Matrix - metabolism Female Humans Immunohistochemistry Interferon-gamma - metabolism Interferon-gamma - pharmacology Killer Cells, Natural - metabolism Killer Cells, Natural - physiology Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - metabolism Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - metabolism Myometrium - cytology Myometrium - metabolism Placenta - cytology Placenta - metabolism Pregnancy Tissue Culture Techniques Trophoblasts - cytology Trophoblasts - metabolism Trophoblasts - physiology Uterine Artery - cytology Uterine Artery - drug effects Uterine Artery - physiology Uterus - blood supply Uterus - cytology Vascular Endothelial Growth Factor C - metabolism Vascular Endothelial Growth Factor C - pharmacology
ISSN:	1530-6860, 1530-6860
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