Uterine natural killer cells initiate spiral artery remodeling in human pregnancy

Uterine spiral artery remodeling is required for successful human pregnancy; impaired remodeling is associated with pregnancy complications, including late miscarriage, preeclampsia, and fetal growth restriction. The molecular triggers of remodeling are not known, but it is now clear that there are...

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Bibliographic Details
Published in:	The FASEB journal Vol. 26; no. 12; p. 4876
Main Authors:	Robson, Andrew, Harris, Lynda K, Innes, Barbara A, Lash, Gendie E, Aljunaidy, Mais M, Aplin, John D, Baker, Philip N, Robson, Stephen C, Bulmer, Judith N
Format:	Journal Article
Language:	English
Published:	United States 01.12.2012
Subjects:	Angiopoietin-1 - metabolism Angiopoietin-1 - pharmacology Angiopoietin-2 - metabolism Angiopoietin-2 - pharmacology Cell Line Cells, Cultured Culture Media, Conditioned - metabolism Culture Media, Conditioned - pharmacology Decidua - cytology Decidua - metabolism Extracellular Matrix - drug effects Extracellular Matrix - metabolism Female Humans Immunohistochemistry Interferon-gamma - metabolism Interferon-gamma - pharmacology Killer Cells, Natural - metabolism Killer Cells, Natural - physiology Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - metabolism Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - metabolism Myometrium - cytology Myometrium - metabolism Placenta - cytology Placenta - metabolism Pregnancy Tissue Culture Techniques Trophoblasts - cytology Trophoblasts - metabolism Trophoblasts - physiology Uterine Artery - cytology Uterine Artery - drug effects Uterine Artery - physiology Uterus - blood supply Uterus - cytology Vascular Endothelial Growth Factor C - metabolism Vascular Endothelial Growth Factor C - pharmacology
ISSN:	1530-6860, 1530-6860
Online Access:	Get more information
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