Prevalence of Gastrointestinal and Cardiovascular Risk in Patients with Degenerative Lumbar Spinal Disease

Limited information is available about the proportion of patients with degenerative lumbar spinal disease (DLSD) who have gastrointestinal (GI) and cardiovascular (CV) risk factors. Many DLSD patients are prescribed nonsteroidal anti-inflammatory drugs (NSAIDs) that are known to carry risks to the G...

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Published in:	Clinics in orthopedic surgery Vol. 12; no. 3; pp. 343 - 352
Main Authors:	Yang, Jae-Ho, Lee, Byoung-Ho, Eum, Kwang-Sik, Suk, Kyoung-Soo, Park, Jin-Oh, Kim, Hak-Sun, Lee, Hwan-Mo, Moon, Seong-Hwan
Format:	Journal Article
Language:	English
Published:	Korea (South) The Korean Orthopaedic Association 01.09.2020 대한정형외과학회
Subjects:	Aged Anti-Inflammatory Agents, Non-Steroidal - adverse effects Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Cardiovascular Diseases - chemically induced Cross-Sectional Studies Female Gastrointestinal Diseases - chemically induced Guideline Adherence Humans Lumbar Vertebrae Male Middle Aged Original Practice Patterns, Physicians Prevalence Retrospective Studies Risk Assessment Risk Factors Spinal Diseases - complications Spinal Diseases - drug therapy 정형외과학 Cardiovascular disease Gastrointestinal disorder Non-steroidal anti-inflammatory agents Spine disease Risk assessment
ISSN:	2005-291X, 2005-4408, 2005-4408
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Abstract	Limited information is available about the proportion of patients with degenerative lumbar spinal disease (DLSD) who have gastrointestinal (GI) and cardiovascular (CV) risk factors. Many DLSD patients are prescribed nonsteroidal anti-inflammatory drugs (NSAIDs) that are known to carry risks to the GI and CV systems by increasing GI bleeding and thromboembolic events. This study aimed to measure the prevalence of GI and CV risk in patients with DLSD and to ascertain whether the prescription of NSAIDs is in line with current guidelines. This study included 153 patients with symptomatic DLSD who were planning to undergo lumbar spinal surgery. The GI profile was checked using the GI Standardized Calculator of Risk for Event system and CV risk was evaluated using the presence of metabolic syndrome. The conformity of the prescription of NSAIDs was investigated according to the recommendations in current guidelines. More than half of the patients (59.5%) had high or very high GI risk, and 66% of the patients were diagnosed with metabolic syndrome, which corresponds with CV risk. The rate of simultaneous GI and CV risk was 40.5% (n = 62 / 153; gastrointestinal Standardized Calculator of Risk for Event, > high and metabolic syndrome, yes). The actual prescription of NSAIDs was not in accordance with current guidelines. Two out of 3 patients had GI or CV risk factors, and approximately 40% of patients had both. Detailed assessment of GI and CV risk in patients with DLSD by using effective evaluation tools is mandatory for optimal medical treatment.
AbstractList	Limited information is available about the proportion of patients with degenerative lumbar spinal disease (DLSD) who have gastrointestinal (GI) and cardiovascular (CV) risk factors. Many DLSD patients are prescribed nonsteroidal anti-inflammatory drugs (NSAIDs) that are known to carry risks to the GI and CV systems by increasing GI bleeding and thromboembolic events. This study aimed to measure the prevalence of GI and CV risk in patients with DLSD and to ascertain whether the prescription of NSAIDs is in line with current guidelines. This study included 153 patients with symptomatic DLSD who were planning to undergo lumbar spinal surgery. The GI profile was checked using the GI Standardized Calculator of Risk for Event system and CV risk was evaluated using the presence of metabolic syndrome. The conformity of the prescription of NSAIDs was investigated according to the recommendations in current guidelines. More than half of the patients (59.5%) had high or very high GI risk, and 66% of the patients were diagnosed with metabolic syndrome, which corresponds with CV risk. The rate of simultaneous GI and CV risk was 40.5% (n = 62 / 153; gastrointestinal Standardized Calculator of Risk for Event, > high and metabolic syndrome, yes). The actual prescription of NSAIDs was not in accordance with current guidelines. Two out of 3 patients had GI or CV risk factors, and approximately 40% of patients had both. Detailed assessment of GI and CV risk in patients with DLSD by using effective evaluation tools is mandatory for optimal medical treatment. Limited information is available about the proportion of patients with degenerative lumbar spinal disease (DLSD) who have gastrointestinal (GI) and cardiovascular (CV) risk factors. Many DLSD patients are prescribed nonsteroidal anti-inflammatory drugs (NSAIDs) that are known to carry risks to the GI and CV systems by increasing GI bleeding and thromboembolic events. This study aimed to measure the prevalence of GI and CV risk in patients with DLSD and to ascertain whether the prescription of NSAIDs is in line with current guidelines.BACKGROUNDLimited information is available about the proportion of patients with degenerative lumbar spinal disease (DLSD) who have gastrointestinal (GI) and cardiovascular (CV) risk factors. Many DLSD patients are prescribed nonsteroidal anti-inflammatory drugs (NSAIDs) that are known to carry risks to the GI and CV systems by increasing GI bleeding and thromboembolic events. This study aimed to measure the prevalence of GI and CV risk in patients with DLSD and to ascertain whether the prescription of NSAIDs is in line with current guidelines.This study included 153 patients with symptomatic DLSD who were planning to undergo lumbar spinal surgery. The GI profile was checked using the GI Standardized Calculator of Risk for Event system and CV risk was evaluated using the presence of metabolic syndrome. The conformity of the prescription of NSAIDs was investigated according to the recommendations in current guidelines.METHODSThis study included 153 patients with symptomatic DLSD who were planning to undergo lumbar spinal surgery. The GI profile was checked using the GI Standardized Calculator of Risk for Event system and CV risk was evaluated using the presence of metabolic syndrome. The conformity of the prescription of NSAIDs was investigated according to the recommendations in current guidelines.More than half of the patients (59.5%) had high or very high GI risk, and 66% of the patients were diagnosed with metabolic syndrome, which corresponds with CV risk. The rate of simultaneous GI and CV risk was 40.5% (n = 62 / 153; gastrointestinal Standardized Calculator of Risk for Event, > high and metabolic syndrome, yes). The actual prescription of NSAIDs was not in accordance with current guidelines.RESULTSMore than half of the patients (59.5%) had high or very high GI risk, and 66% of the patients were diagnosed with metabolic syndrome, which corresponds with CV risk. The rate of simultaneous GI and CV risk was 40.5% (n = 62 / 153; gastrointestinal Standardized Calculator of Risk for Event, > high and metabolic syndrome, yes). The actual prescription of NSAIDs was not in accordance with current guidelines.Two out of 3 patients had GI or CV risk factors, and approximately 40% of patients had both. Detailed assessment of GI and CV risk in patients with DLSD by using effective evaluation tools is mandatory for optimal medical treatment.CONCLUSIONSTwo out of 3 patients had GI or CV risk factors, and approximately 40% of patients had both. Detailed assessment of GI and CV risk in patients with DLSD by using effective evaluation tools is mandatory for optimal medical treatment. Background: Limited information is available about the proportion of patients with degenerative lumbar spinal disease (DLSD) who have gastrointestinal (GI) and cardiovascular (CV) risk factors. Many DLSD patients are prescribed nonsteroidal anti-inflammatory drugs (NSAIDs) that are known to carry risks to the GI and CV systems by increasing GI bleeding and thromboembolic events. This study aimed to measure the prevalence of GI and CV risk in patients with DLSD and to ascertain whether the prescription of NSAIDs is in line with current guidelines. Methods: This study included 153 patients with symptomatic DLSD who were planning to undergo lumbar spinal surgery. The GI profile was checked using the GI Standardized Calculator of Risk for Event system and CV risk was evaluated using the presence of metabolic syndrome. The conformity of the prescription of NSAIDs was investigated according to the recommendations in current guidelines. Results: More than half of the patients (59.5%) had high or very high GI risk, and 66% of the patients were diagnosed with metabolic syndrome, which corresponds with CV risk. The rate of simultaneous GI and CV risk was 40.5% (n = 62 / 153; gastrointestinal Standardized Calculator of Risk for Event, > high and metabolic syndrome, yes). The actual prescription of NSAIDs was not in accordance with current guidelines. Conclusions: Two out of 3 patients had GI or CV risk factors, and approximately 40% of patients had both. Detailed assessment of GI and CV risk in patients with DLSD by using effective evaluation tools is mandatory for optimal medical treatment. KCI Citation Count: 0
Author	Eum, Kwang-Sik Suk, Kyoung-Soo Yang, Jae-Ho Park, Jin-Oh Lee, Hwan-Mo Kim, Hak-Sun Lee, Byoung-Ho Moon, Seong-Hwan
AuthorAffiliation	Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea
AuthorAffiliation_xml	– name: Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea
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Cites_doi	10.1097/00007632-200010010-00013 10.1016/j.spinee.2013.06.069 10.1253/circj.CJ-12-1573 10.1136/ard.2009.123166 10.18553/jmcp.2002.8.4.252 10.1371/journal.pmed.1001098 10.1111/j.1742-7843.2006.pto_302.x 10.1001/jama.285.19.2486 10.1161/CIRCULATIONAHA.105.568451 10.1016/j.diabres.2006.04.013 10.31616/asj.2019.0125 10.31616/asj.2019.0046 10.1016/0002-9343(91)90118-H 10.3346/jkms.2011.26.4.561 10.1016/j.cgh.2007.03.011 10.1093/oxfordjournals.aje.a009572 10.1136/bmj.c7086 10.1016/j.bpg.2009.11.005 10.1007/s40261-013-0052-6 10.1136/bmj.332.7553.1302 10.1161/CIRCULATIONAHA.108.764530 10.1186/ar1795 10.1007/s00535-008-2275-5 10.1001/jama.287.3.356 10.2337/diacare.26.11.3160 10.1186/1741-7015-3-17 10.2337/diacare.24.4.683 10.1007/s10067-008-0952-7 10.1007/s11938-006-0033-4 10.1186/1471-2458-13-603
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Keywords	Cardiovascular disease Gastrointestinal disorder Non-steroidal anti-inflammatory agents Spine disease Risk assessment
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References	Kim (10.4055/cios20021_ref2) 2020; 14 Trelle (10.4055/cios20021_ref19) 2011; 342 Rostom (10.4055/cios20021_ref11) 2007; 5 Kim (10.4055/cios20021_ref32) 2013; 13 Bull (10.4055/cios20021_ref23) 2002; 8 Patricio (10.4055/cios20021_ref3) 2013; 33 Rahyussalim (10.4055/cios20021_ref1) 2020; 14 Lee (10.4055/cios20021_ref28) 2007; 75 Lanza (10.4055/cios20021_ref21) 2009; 104 Fries (10.4055/cios20021_ref22) 1991; 91 Solomon (10.4055/cios20021_ref12) 2008; 117 Lanas (10.4055/cios20021_ref8) 2006; 9 Isomaa (10.4055/cios20021_ref25) 2001; 24 Scheiman (10.4055/cios20021_ref5) 2005; 7 Suppl 4 van Tulder (10.4055/cios20021_ref4) 2000; 25 McGettigan (10.4055/cios20021_ref18) 2011; 8 Genuth (10.4055/cios20021_ref29) 2003; 26 Gene (10.4055/cios20021_ref10) 2009; 21 Lanas (10.4055/cios20021_ref20) 2010; 69 Hirayama (10.4055/cios20021_ref16) 2014; 78 Ford (10.4055/cios20021_ref24) 2002; 287 Han (10.4055/cios20021_ref31) 2013; 13 Kearney (10.4055/cios20021_ref15) 2006; 332 Juby (10.4055/cios20021_ref6) 2008; 27 Lee (10.4055/cios20021_ref30) 2011; 26 Hernandez-Diaz (10.4055/cios20021_ref17) 2006; 98 Garcia Rodriguez (10.4055/cios20021_ref13) 2005; 3 Antman (10.4055/cios20021_ref14) 2005; 112 Sostres (10.4055/cios20021_ref7) 2010; 24 Trevisan (10.4055/cios20021_ref26) 1998; 148 Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (10.4055/cios20021_ref27) 2001; 285 Schlansky (10.4055/cios20021_ref9) 2009; 44 Suppl 19
References_xml	– volume: 25 start-page: 2501 issue: 19 year: 2000 ident: 10.4055/cios20021_ref4 publication-title: Spine (Phila Pa 1976) doi: 10.1097/00007632-200010010-00013 – volume: 13 start-page: 1230 issue: 10 year: 2013 ident: 10.4055/cios20021_ref32 publication-title: Spine J doi: 10.1016/j.spinee.2013.06.069 – volume: 104 start-page: 728 issue: 3 year: 2009 ident: 10.4055/cios20021_ref21 publication-title: Am J Gastroenterol – volume: 78 start-page: 194 issue: 1 year: 2014 ident: 10.4055/cios20021_ref16 publication-title: Circ J doi: 10.1253/circj.CJ-12-1573 – volume: 69 start-page: 1453 issue: 8 year: 2010 ident: 10.4055/cios20021_ref20 publication-title: Ann Rheum Dis doi: 10.1136/ard.2009.123166 – volume: 8 start-page: 252 issue: 4 year: 2002 ident: 10.4055/cios20021_ref23 publication-title: J Manag Care Pharm doi: 10.18553/jmcp.2002.8.4.252 – volume: 8 start-page: e1001098 issue: 9 year: 2011 ident: 10.4055/cios20021_ref18 publication-title: PLoS Med doi: 10.1371/journal.pmed.1001098 – volume: 98 start-page: 266 issue: 3 year: 2006 ident: 10.4055/cios20021_ref17 publication-title: Basic Clin Pharmacol Toxicol doi: 10.1111/j.1742-7843.2006.pto_302.x – volume: 285 start-page: 2486 issue: 19 year: 2001 ident: 10.4055/cios20021_ref27 publication-title: JAMA doi: 10.1001/jama.285.19.2486 – volume: 112 start-page: 759 issue: 5 year: 2005 ident: 10.4055/cios20021_ref14 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.105.568451 – volume: 75 start-page: 72 issue: 1 year: 2007 ident: 10.4055/cios20021_ref28 publication-title: Diabetes Res Clin Pract doi: 10.1016/j.diabres.2006.04.013 – volume: 14 start-page: 364 issue: 3 year: 2020 ident: 10.4055/cios20021_ref2 publication-title: Asian Spine J doi: 10.31616/asj.2019.0125 – volume: 21 start-page: 295 issue: 4 year: 2009 ident: 10.4055/cios20021_ref10 publication-title: Emergencias – volume: 14 start-page: 245 issue: 2 year: 2020 ident: 10.4055/cios20021_ref1 publication-title: Asian Spine J doi: 10.31616/asj.2019.0046 – volume: 91 start-page: 213 issue: 3 year: 1991 ident: 10.4055/cios20021_ref22 publication-title: Am J Med doi: 10.1016/0002-9343(91)90118-H – volume: 26 start-page: 561 issue: 4 year: 2011 ident: 10.4055/cios20021_ref30 publication-title: J Korean Med Sci doi: 10.3346/jkms.2011.26.4.561 – volume: 5 start-page: 818 issue: 7 year: 2007 ident: 10.4055/cios20021_ref11 publication-title: Clin Gastroenterol Hepatol doi: 10.1016/j.cgh.2007.03.011 – volume: 148 start-page: 958 issue: 10 year: 1998 ident: 10.4055/cios20021_ref26 publication-title: Am J Epidemiol doi: 10.1093/oxfordjournals.aje.a009572 – volume: 342 start-page: c7086 year: 2011 ident: 10.4055/cios20021_ref19 publication-title: BMJ doi: 10.1136/bmj.c7086 – volume: 24 start-page: 121 issue: 2 year: 2010 ident: 10.4055/cios20021_ref7 publication-title: Best Pract Res Clin Gastroenterol doi: 10.1016/j.bpg.2009.11.005 – volume: 33 start-page: 167 issue: 3 year: 2013 ident: 10.4055/cios20021_ref3 publication-title: Clin Drug Investig doi: 10.1007/s40261-013-0052-6 – volume: 332 start-page: 1302 issue: 7553 year: 2006 ident: 10.4055/cios20021_ref15 publication-title: BMJ doi: 10.1136/bmj.332.7553.1302 – volume: 117 start-page: 2104 issue: 16 year: 2008 ident: 10.4055/cios20021_ref12 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.108.764530 – volume: 7 Suppl 4 start-page: S23 issue: Suppl 4 year: 2005 ident: 10.4055/cios20021_ref5 publication-title: Arthritis Res Ther doi: 10.1186/ar1795 – volume: 44 Suppl 19 start-page: 44 year: 2009 ident: 10.4055/cios20021_ref9 publication-title: J Gastroenterol doi: 10.1007/s00535-008-2275-5 – volume: 287 start-page: 356 issue: 3 year: 2002 ident: 10.4055/cios20021_ref24 publication-title: JAMA doi: 10.1001/jama.287.3.356 – volume: 26 start-page: 3160 issue: 11 year: 2003 ident: 10.4055/cios20021_ref29 publication-title: Diabetes Care doi: 10.2337/diacare.26.11.3160 – volume: 3 start-page: 17 year: 2005 ident: 10.4055/cios20021_ref13 publication-title: BMC Med doi: 10.1186/1741-7015-3-17 – volume: 24 start-page: 683 issue: 4 year: 2001 ident: 10.4055/cios20021_ref25 publication-title: Diabetes Care doi: 10.2337/diacare.24.4.683 – volume: 27 start-page: 1191 issue: 9 year: 2008 ident: 10.4055/cios20021_ref6 publication-title: Clin Rheumatol doi: 10.1007/s10067-008-0952-7 – volume: 9 start-page: 147 issue: 2 year: 2006 ident: 10.4055/cios20021_ref8 publication-title: Curr Treat Options Gastroenterol doi: 10.1007/s11938-006-0033-4 – volume: 13 start-page: 603 year: 2013 ident: 10.4055/cios20021_ref31 publication-title: BMC Public Health doi: 10.1186/1471-2458-13-603
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SubjectTerms	Aged Anti-Inflammatory Agents, Non-Steroidal - adverse effects Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Cardiovascular Diseases - chemically induced Cross-Sectional Studies Female Gastrointestinal Diseases - chemically induced Guideline Adherence Humans Lumbar Vertebrae Male Middle Aged Original Practice Patterns, Physicians Prevalence Retrospective Studies Risk Assessment Risk Factors Spinal Diseases - complications Spinal Diseases - drug therapy 정형외과학
Title	Prevalence of Gastrointestinal and Cardiovascular Risk in Patients with Degenerative Lumbar Spinal Disease
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