Absorption, distribution, metabolism, and excretion of ticagrelor in healthy subjects

Ticagrelor [(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl) cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol)] is a reversibly binding oral P2Y(12) receptor antagonist in development for the prevention of thrombotic events in pati...

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Vydané v:	Drug metabolism and disposition Ročník 38; číslo 9; s. 1514
Hlavní autori:	Teng, Renli, Oliver, Stuart, Hayes, Martin A, Butler, Kathleen
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.09.2010
Predmet:	Adenosine - administration & dosage Adenosine - analogs & derivatives Adenosine - pharmacokinetics Administration, Oral Adult Chromatography, Liquid Humans Male Middle Aged Purinergic Antagonists - administration & dosage Purinergic Antagonists - pharmacokinetics Reference Values Tandem Mass Spectrometry Ticagrelor
ISSN:	1521-009X, 1521-009X
On-line prístup:	Zistit podrobnosti o prístupe
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