Pharmacological treatment of the biochemical defect in cystic fibrosis airways

The understanding of the biochemical defect in cystic fibrosis (CF) has advanced considerably since discovery of the CF gene in 1989 and characterization of its product. Studies showing that the abnormality in chloride flux could be corrected by transfection of wild-type cystic fibrosis transmembran...

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Veröffentlicht in:	The European respiratory journal Jg. 17; H. 6; S. 1314
Hauptverfasser:	Rodgers, H C, Knox, A J
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.06.2001
Schlagworte:	Animals Chloride Channels - drug effects Chloride Channels - genetics Chloride Channels - physiology Cystic Fibrosis - drug therapy Cystic Fibrosis - genetics Cystic Fibrosis - physiopathology Cystic Fibrosis Transmembrane Conductance Regulator - genetics DNA Mutational Analysis Humans Sodium Channel Blockers - adverse effects Sodium Channel Blockers - therapeutic use Sodium Channels - drug effects Sodium Channels - genetics Sodium Channels - physiology
ISSN:	0903-1936
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