Human immunodeficiency virus type 1 RNA Levels in different regions of human brain: Quantification using real-time reverse transcriptase-polymerase chain reaction

Human immunodeficiency virus type 1 (HIV-1) enters the central nervous system shortly after the infection and becomes localized in different regions of the brain, leading to various neurological abnormalities including motor disorders and neurocognitive deficits. Although HIV-1-associated functional...

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Vydané v:	Journal of neurovirology Ročník 13; číslo 3; s. 210 - 224
Hlavní autori:	Kumar, Adarsh M, Borodowsky, Irina, Fernandez, Benny, Gonzalez, Louis, Kumar, Mahendra
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London Informa UK Ltd 01.01.2007 Taylor & Francis Nature Publishing Group
Predmet:	Adult Aged AIDS Dementia Complex - virology Autopsies Autopsy Basal ganglia Biological and medical sciences Brain Brain - virology Caudate nucleus Caudate Nucleus - virology Central nervous system Cerebrospinal fluid Cognition Cortex (frontal) DNA probes Female Frontal Lobe - virology Globus pallidus Globus Pallidus - virology Highly active antiretroviral therapy HIV HIV-1 - genetics Human immunodeficiency virus Human viral diseases Humans Immune system Infectious diseases Long terminal repeat Male Medical sciences Middle Aged Movement disorders Nervous system Neurological diseases Neuropathogenesis Polymerase chain reaction Putamen Putamen - virology Reverse Transcriptase Polymerase Chain Reaction Ribonucleic acid RNA RNA viruses RNA, Viral - cerebrospinal fluid RNA, Viral - genetics RNA-directed DNA polymerase Sensitivity and Specificity Substantia nigra Substantia Nigra - virology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral diseases of the nervous system Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye Viral Load Human brain regions Nervous system diseases RNA-directed DNA polymerase HIV-1 virus Enzyme Transferases Central nervous system HIV-1 RNA Retroviridae real-time RT-PCR Lentivirus Encephalon Infection Virus Polymerase chain reaction Nucleotidyltransferases Viral disease Human immunodeficiency virus Reverse transcription polymerase chain reaction
ISSN:	1355-0284, 1538-2443
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