Virus Variation Resource – improved response to emergent viral outbreaks

The Virus Variation Resource is a value-added viral sequence data resource hosted by the National Center for Biotechnology Information. The resource is located at http://www.ncbi.nlm.nih.gov/genome/viruses/variation/ and includes modules for seven viral groups: influenza virus, Dengue virus, West Ni...

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Bibliographic Details
Published in:Nucleic acids research Vol. 45; no. D1; pp. D482 - D490
Main Authors: Hatcher, Eneida L., Zhdanov, Sergey A., Bao, Yiming, Blinkova, Olga, Nawrocki, Eric P., Ostapchuck, Yuri, Schäffer, Alejandro A., Brister, J. Rodney
Format: Journal Article
Language:English
Published: England Oxford University Press 04.01.2017
Subjects:
Computational Biology - methods
Database Issue
Databases, Genetic
Disease Outbreaks
Genetic Variation
Software
Virus Diseases - epidemiology
Virus Diseases - virology
Viruses - genetics
ISSN:0305-1048, 1362-4962, 1362-4962
Online Access:Get full text
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Summary:The Virus Variation Resource is a value-added viral sequence data resource hosted by the National Center for Biotechnology Information. The resource is located at http://www.ncbi.nlm.nih.gov/genome/viruses/variation/ and includes modules for seven viral groups: influenza virus, Dengue virus, West Nile virus, Ebolavirus, MERS coronavirus, Rotavirus A and Zika virus Each module is supported by pipelines that scan newly released GenBank records, annotate genes and proteins and parse sample descriptors and then map them to controlled vocabulary. These processes in turn support a purpose-built search interface where users can select sequences based on standardized gene, protein and metadata terms. Once sequences are selected, a suite of tools for downloading data, multi-sequence alignment and tree building supports a variety of user directed activities. This manuscript describes a series of features and functionalities recently added to the Virus Variation Resource.
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ISSN:0305-1048
1362-4962
1362-4962
DOI:10.1093/nar/gkw1065