A Hybrid Barnacles Mating Optimizer Algorithm With Support Vector Machines for Gene Selection of Microarray Cancer Classification

These days, the classification between normal and cancerous tissues and between different types of cancers represents a very important issue. Selecting the little informative number of genes is considered the main challenge in the cancer diagnosis issue. Therefore, Gene selection is usually the prel...

Celý popis

Uložené v:
Podrobná bibliografia
Vydané v:IEEE access Ročník 9; s. 64895 - 64905
Hlavní autori: Houssein, Essam H., Abdelminaam, Diaa Salama, Hassan, Hager N., Al-Sayed, Mustafa M., Nabil, Emad
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Piscataway IEEE 2021
The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Predmet:
barnacles mating optimizer algorithm
Cancer
Classification
Datasets
feature selection
Gene expression
Gene selection
Genes
Genetic algorithms
Heuristic methods
Mathematical model
microarray cancer classification
Optimization
Optimization algorithms
Optimization techniques
Particle swarm optimization
Prediction algorithms
Support vector machines
ISSN:2169-3536, 2169-3536
On-line prístup:Získať plný text
Tagy: Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
Popis
Shrnutí:These days, the classification between normal and cancerous tissues and between different types of cancers represents a very important issue. Selecting the little informative number of genes is considered the main challenge in the cancer diagnosis issue. Therefore, Gene selection is usually the preliminary step for solving the cancer classification problems. Bio-inspired metaheuristic optimization algorithms, when used to solve gene selection and classification problems, they demonstrate their effectiveness. Barnacles Mating Optimizer (BMO) algorithm, which imitates the behavior of mating barnacles in nature for solving optimization problems, is considered one of these algorithms. In this paper, Barnacles Mating Optimizer (BMO) algorithm augmented with Support Vector Machines (SVM) called BMO-SVM is proposed for a microarray gene expression profiling in order to select the most predictive and informative genes for cancer classification. Conducting a comparative experimental study among a set of the most common bio-inspired optimization techniques to specify the most effective. A binary microarray dataset (i.e., leukemia1) and a multi-class microarray dataset (i.e., SRBCT, lymphoma, and leukemia2) are used for testing the performance of the proposed model. The experimental results revealed the superiority of the proposed BMO-SVM approach against several well-known meta-heuristic optimization algorithms, such as the Tunicate Swarm Algorithm (TSA), Genetic Algorithm (GA), Particle Swarm Optimization (PSO), and Artificial Bee Colony (ABC). It is worth mentioning that our proposed algorithm achieves a high informational superiority percentage compared to other algorithms.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ISSN:2169-3536
2169-3536
DOI:10.1109/ACCESS.2021.3075942