Association of periodontal infections with atherosclerotic and pulmonary diseases

Chronic infections may influence the severity and/or course of a number of systemic diseases. Periodontal diseases are localized chronic inflammatory conditions of the gingiva and underlying bone and connective tissues induced by bacteria and bacterial products of dental plaque. This paper will disc...

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Published in:	Journal of periodontal research Vol. 34; no. 7; pp. 340 - 345
Main Authors:	Scannapieco, F. A., Genco, R. J.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01.10.1999
Subjects:	Alveolar Process - microbiology Arteriosclerosis - etiology Bacterial Infections Brain Ischemia - etiology cardiovascular disease Chronic Disease chronic obstructive pulmonary disease Connective Tissue - microbiology coronary artery disease Coronary Disease - etiology Dental Plaque - microbiology Gingivitis - microbiology Humans Lung Diseases - etiology Periodontal Diseases - microbiology pneumonia Respiratory Tract Infections - microbiology Stroke - etiology
ISSN:	0022-3484, 1600-0765
Online Access:	Get full text
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Abstract	Chronic infections may influence the severity and/or course of a number of systemic diseases. Periodontal diseases are localized chronic inflammatory conditions of the gingiva and underlying bone and connective tissues induced by bacteria and bacterial products of dental plaque. This paper will discuss the evidence for the role of periodontal disease in the pathogenesis of 2 important systemic diseases, atherosclerosis and pulmonary infections. Both epidemiological and laboratory studies are reviewed to assess the biological basis for the association of periodontal infections and these important diseases. Several potential mechanisms by which periodontal diseases may influence these conditions are also discussed.
AbstractList	Chronic infections may influence the severity and/or course of a number of systemic diseases. Periodontal diseases are localized chronic inflammatory conditions of the gingiva and underlying bone and connective tissues induced by bacteria and bacterial products of dental plaque. This paper will discuss the evidence for the role of periodontal disease in the pathogenesis of 2 important systemic diseases, atherosclerosis and pulmonary infections. Both epidemiological and laboratory studies are reviewed to assess the biological basis for the association of periodontal infections and these important diseases. Several potential mechanisms by which periodontal diseases may influence these conditions are also discussed. Chronic infections may influence the severity and/or course of a number of systemic diseases. Periodontal diseases are localized chronic inflammatory conditions of the gingiva and underlying bone and connective tissues induced by bacteria and bacterial products of dental plaque. This paper will discuss the evidence for the role of periodontal disease in the pathogenesis of 2 important systemic diseases, atherosclerosis and pulmonary infections. Both epidemiological and laboratory studies are reviewed to assess the biological basis for the association of periodontal infections and these important diseases. Several potential mechanisms by which periodontal diseases may influence these conditions are also discussed.Chronic infections may influence the severity and/or course of a number of systemic diseases. Periodontal diseases are localized chronic inflammatory conditions of the gingiva and underlying bone and connective tissues induced by bacteria and bacterial products of dental plaque. This paper will discuss the evidence for the role of periodontal disease in the pathogenesis of 2 important systemic diseases, atherosclerosis and pulmonary infections. Both epidemiological and laboratory studies are reviewed to assess the biological basis for the association of periodontal infections and these important diseases. Several potential mechanisms by which periodontal diseases may influence these conditions are also discussed.
Author	Scannapieco, F. A. Genco, R. J.
Author_xml	– sequence: 1 givenname: F. A. surname: Scannapieco fullname: Scannapieco, F. A. email: fas1@acsu.buffalo.edu organization: Department of Oral Biology, University at Buffalo, Slate University of New York, Buffalo, NY, USA – sequence: 2 givenname: R. J. surname: Genco fullname: Genco, R. J. organization: Department of Oral Biology, University at Buffalo, Slate University of New York, Buffalo, NY, USA
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/10685358$$D View this record in MEDLINE/PubMed
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Heat shock protein 60 (GroEL) from Porphyromonas gingivali 1991; 13 1997; 350 1997; 156 1981; 143 1999; 45 1999; 283 1998; 279 1983; 18 1997; 3 1985; 20 1996; 75 1996; 31 1995; 20 1997; 349 1997; 107 1990 1999; 19 1997; 14 1995; 21 1999; 99 1998; 98 1998; 167 1996; 67 1998; 26 1979; 19 1997; 337 1993; 306 1989; 255 1992; 146 1992; 268 1999; 26 1989; 298 1999; 340 1997; 28 1994 1993 1993; 103 1995; 152 1998; 66 1999 1996; 11 1993; 14 1994; 124 1995; 40 1984; 30 1969; 281 1968; 39 1997; 76 1986; 21 1988; 7 1999; 78 1986; 291 1998; 3 1998; 147 1992; 20 1996; 797 1999; 70 1994; 5 1998; 77 Haraszthy VI (e_1_2_1_20_2) 1998; 77 Wu T (e_1_2_1_30_2) 1999 e_1_2_1_41_2 e_1_2_1_64_2 Schreiner A. (e_1_2_1_45_2) 1979; 19 e_1_2_1_66_2 e_1_2_1_60_2 e_1_2_1_43_2 e_1_2_1_62_2 e_1_2_1_26_2 e_1_2_1_49_2 e_1_2_1_24_2 e_1_2_1_47_2 e_1_2_1_68_2 e_1_2_1_28_2 Wu T (e_1_2_1_19_2) 1998; 147 e_1_2_1_6_2 e_1_2_1_54_2 e_1_2_1_56_2 e_1_2_1_2_2 Genco RJ (e_1_2_1_16_2) 1997; 76 e_1_2_1_12_2 e_1_2_1_33_2 e_1_2_1_10_2 e_1_2_1_31_2 e_1_2_1_52_2 Paunio K (e_1_2_1_11_2) 1993; 14 e_1_2_1_14_2 Limeback H. (e_1_2_1_50_2) 1988; 7 e_1_2_1_58_2 e_1_2_1_8_2 e_1_2_1_18_2 Society AT. (e_1_2_1_35_2) 1995; 152 e_1_2_1_40_2 e_1_2_1_65_2 (e_1_2_1_4_2) 1993 e_1_2_1_67_2 e_1_2_1_23_2 Donowitz GR (e_1_2_1_39_2) 1990 e_1_2_1_44_2 e_1_2_1_61_2 Deshpande RG (e_1_2_1_22_2) 1998; 66 Fagon JY (e_1_2_1_37_2) 1996; 11 e_1_2_1_42_2 Levison ME. (e_1_2_1_46_2) 1994 e_1_2_1_63_2 Chiu B (e_1_2_1_21_2) 1999 e_1_2_1_27_2 e_1_2_1_48_2 e_1_2_1_25_2 e_1_2_1_29_2 Scannapieco FA (e_1_2_1_57_2) 1999; 78 Thorn DH (e_1_2_1_7_2) 1992; 268 e_1_2_1_53_2 e_1_2_1_55_2 e_1_2_1_5_2 e_1_2_1_34_2 e_1_2_1_3_2 e_1_2_1_32_2 e_1_2_1_51_2 e_1_2_1_15_2 e_1_2_1_38_2 e_1_2_1_13_2 e_1_2_1_36_2 e_1_2_1_17_2 e_1_2_1_59_2 e_1_2_1_9_2
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Snippet	Chronic infections may influence the severity and/or course of a number of systemic diseases. Periodontal diseases are localized chronic inflammatory...
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SubjectTerms	Alveolar Process - microbiology Arteriosclerosis - etiology Bacterial Infections Brain Ischemia - etiology cardiovascular disease Chronic Disease chronic obstructive pulmonary disease Connective Tissue - microbiology coronary artery disease Coronary Disease - etiology Dental Plaque - microbiology Gingivitis - microbiology Humans Lung Diseases - etiology Periodontal Diseases - microbiology pneumonia Respiratory Tract Infections - microbiology Stroke - etiology
Title	Association of periodontal infections with atherosclerotic and pulmonary diseases
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