Health-related quality of life after colorectal cancer in England: a patient-reported outcomes study of individuals 12 to 36 months after diagnosis

This population-level study was conducted to define the health-related quality of life (HRQL) of individuals living with and beyond colorectal cancer (CRC) and to identify factors associated with poor health outcomes. All individuals diagnosed with CRC in England in 2010 and 2011 who were alive 12 t...

Celý popis

Uložené v:
Podrobná bibliografia
Vydané v:Journal of clinical oncology Ročník 33; číslo 6; s. 616
Hlavní autori: Downing, Amy, Morris, Eva J A, Richards, Mike, Corner, Jessica, Wright, Penny, Sebag-Montefiore, David, Finan, Paul, Kind, Paul, Wood, Charlotte, Lawton, Sarah, Feltbower, Richard, Wagland, Richard, Vernon, Sally, Thomas, James, Glaser, Adam W
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 20.02.2015
Predmet:
Age Factors
Aged
Aged, 80 and over
Colorectal Neoplasms - epidemiology
Colorectal Neoplasms - physiopathology
Colorectal Neoplasms - psychology
England - epidemiology
Female
Humans
Male
Middle Aged
Quality of Life
Self Report
Surveys and Questionnaires
England
ISSN:1527-7755, 1527-7755
On-line prístup:Zistit podrobnosti o prístupe
Tagy: Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
Popis
Shrnutí:This population-level study was conducted to define the health-related quality of life (HRQL) of individuals living with and beyond colorectal cancer (CRC) and to identify factors associated with poor health outcomes. All individuals diagnosed with CRC in England in 2010 and 2011 who were alive 12 to 36 months after diagnosis were sent a questionnaire. This included questions related to treatment, disease status, other long-term conditions (LTCs), generic HRQL (EuroQol-5D), and cancer-specific outcomes (Functional Assessment of Cancer Therapy and Social Difficulties Inventory items). The response rate was 63.3% (21,802 of 34,467 patients). One or more generic health problems were reported by 65% of respondents, with 10% of patients reporting problems in all five domains. The reporting of problems was higher than in the general population and was most marked in those age less than 55 years. Certain subgroups reported a higher number of problems, notably those with one or more other LTCs, those with active or recurrent disease, those with a stoma, and those at the extremes of the age range (< 55 and > 85 years). Of respondents without a stoma, 16.3% reported no bowel control. Reversal of a stoma resulted in fewer severe bowel problems but more moderate problems than those who had never had a stoma. A quarter of rectal cancer respondents (25.1%) reported difficulties with sexual matters (compared with 11.2% of colon cancer respondents). This study demonstrates the success of a national patient-reported outcomes survey. The results have the potential to support system-wide improvement in health outcomes through the identification of particular challenges faced by individuals after treatment for CRC.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1527-7755
1527-7755
DOI:10.1200/JCO.2014.56.6539