Changes in nano-mechanical properties of human epidermal cornified cells in children with atopic dermatitis

Background:  Impaired skin barrier is an important etiological factor in atopic dermatitis (AD). The structural protein filaggrin (FLG) plays a major role in maintenance of the competent skin barrier and its deficiency is associated with enhanced susceptibility to mechanical injury. Here we examined...

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Vydané v:	Wellcome open research Ročník 5; s. 97
Hlavní autori:	Haftek, Marek, McAleer, Maeve A, Jakasa, Ivone, McLean, WH Irwin, Kezic, Sanja, Irvine, Alan D.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London Wellcome Trust Limited 2020 F1000 Research Limited Wellcome
Predmet:	Dermatitis Eczema Humidity Keratin Lipids Mechanical properties Microscopy Mutation Peer review Permeability Skin Skin diseases Germany
ISSN:	2398-502X, 2398-502X
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