UPLC-MS/MS analysis of antibiotics in pharmaceutical effluent in Tunisia: ecotoxicological impact and multi-resistant bacteria dissemination

The UPLC MS/MS analysis showed the presence of the two antibiotics in the pharmaceutical industry discharges during 3 months; norfloxacin and spiramycin which were quantified with the mean concentrations of 226.7 and 84.2 ng mL −1 , respectively. Sixteen resistant isolates were obtained from the pha...

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Bibliographic Details
Published in:	Archives of microbiology Vol. 200; no. 4; pp. 553 - 565
Main Authors:	Tahrani, Leyla, Mehri, Ines, Reyns, Tim, Anthonissen, Roel, Verschaeve, Luc, Khalifa, Anis Bel Haj, Loco, Joris Van, Abdenaceur, Hassen, Mansour, Hedi Ben
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01.05.2018 Springer Nature B.V
Subjects:	Acinetobacter Aminoglycosides Amoxicillin antibiotic residues Antibiotic resistance Antibiotics Bacteria bioassays Biochemistry Biomedical and Life Sciences Bioremediation Biotechnology Cell Biology Ciprofloxacin Citrobacter Cytolysis Damage assessment Delftia Deoxyribonucleic acid DNA DNA damage Ecology ecotoxicology Edema Effluents Genotoxicity Gentamicin Histology Kidneys Life Sciences Liver Marine environment Medical wastes mice Microbial Ecology Microbiology Micronuclei mutagens necrosis Norfloxacin Original Paper Pharmaceutical industry Pharmaceutical industry wastes Pharmaceuticals phenotype Pseudomonas Quinolones Rheinheimera Shewanella Spiramycin tandem mass spectrometry Tunisia ultra-performance liquid chromatography Wastewater Tunisia Biotests Antibiotic multi-resistance UPLC-MSMS Pharmaceutical effluent Genotoxicity
ISSN:	0302-8933, 1432-072X, 1432-072X
Online Access:	Get full text
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