Targeting neuropeptide receptors for cancer imaging and therapy: perspectives with bombesin, neurotensin, and neuropeptide-Y receptors

Receptors for some regulatory peptides are highly expressed in tumors. Selective radiolabeled peptides can bind with high affinity and specificity to these receptors and exhibit favorable pharmacologic and pharmacokinetic properties, making them suitable agents for imaging or targeted therapy. The s...

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Vydané v:	The Journal of nuclear medicine (1978) Ročník 55; číslo 10; s. 1650
Hlavní autori:	Morgat, Clément, Mishra, Anil Kumar, Varshney, Raunak, Allard, Michèle, Fernandez, Philippe, Hindié, Elif
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.10.2014
Predmet:	Breast Neoplasms - diagnosis Breast Neoplasms - drug therapy Female Humans Lung Neoplasms - diagnosis Lung Neoplasms - drug therapy Male Peptides - chemistry Positron-Emission Tomography - methods Prostatic Neoplasms - diagnosis Prostatic Neoplasms - drug therapy Receptors, Bombesin - chemistry Receptors, Neuropeptide Y - chemistry Receptors, Neurotensin - chemistry Tomography, X-Ray Computed - methods neurotensin receptor neuropeptide Y radiopharmaceutical cancer molecular imaging PET bombesin peptide/neuropeptide
ISSN:	1535-5667, 1535-5667
On-line prístup:	Zistit podrobnosti o prístupe
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