Targeting neuropeptide receptors for cancer imaging and therapy: perspectives with bombesin, neurotensin, and neuropeptide-Y receptors

Receptors for some regulatory peptides are highly expressed in tumors. Selective radiolabeled peptides can bind with high affinity and specificity to these receptors and exhibit favorable pharmacologic and pharmacokinetic properties, making them suitable agents for imaging or targeted therapy. The s...

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Bibliographic Details
Published in:	The Journal of nuclear medicine (1978) Vol. 55; no. 10; p. 1650
Main Authors:	Morgat, Clément, Mishra, Anil Kumar, Varshney, Raunak, Allard, Michèle, Fernandez, Philippe, Hindié, Elif
Format:	Journal Article
Language:	English
Published:	United States 01.10.2014
Subjects:	Breast Neoplasms - diagnosis Breast Neoplasms - drug therapy Female Humans Lung Neoplasms - diagnosis Lung Neoplasms - drug therapy Male Peptides - chemistry Positron-Emission Tomography - methods Prostatic Neoplasms - diagnosis Prostatic Neoplasms - drug therapy Receptors, Bombesin - chemistry Receptors, Neuropeptide Y - chemistry Receptors, Neurotensin - chemistry Tomography, X-Ray Computed - methods neurotensin receptor neuropeptide Y radiopharmaceutical cancer molecular imaging PET bombesin peptide/neuropeptide
ISSN:	1535-5667, 1535-5667
Online Access:	Get more information
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