Multidrug-resistant tuberculosis (TB) resistant to fluoroquinolones and streptomycin but susceptible to second-line injection therapy has a better prognosis than extensively drug-resistant TB

Multidrug-resistant tuberculosis (TB) strains resistant to the fluoroquinolones and streptomycin but susceptible to second-line injection treatment would not be defined as extensively drug-resistant TB. In a cohort of 174 patients with multidrug-resistant TB, we demonstrated that 12 patients with mu...

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Vydáno v:Clinical infectious diseases Ročník 48; číslo 5; s. e50
Hlavní autoři: Chan, Edward D, Strand, Matthew J, Iseman, Michael D
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 01.03.2009
Témata:
Antitubercular Agents - therapeutic use
Cohort Studies
Extensively Drug-Resistant Tuberculosis - diagnosis
Extensively Drug-Resistant Tuberculosis - drug therapy
Fluoroquinolones - therapeutic use
Humans
Prognosis
Streptomycin - therapeutic use
Treatment Outcome
Tuberculosis, Multidrug-Resistant - diagnosis
Tuberculosis, Multidrug-Resistant - drug therapy
ISSN:1537-6591, 1537-6591
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Shrnutí:Multidrug-resistant tuberculosis (TB) strains resistant to the fluoroquinolones and streptomycin but susceptible to second-line injection treatment would not be defined as extensively drug-resistant TB. In a cohort of 174 patients with multidrug-resistant TB, we demonstrated that 12 patients with multidrug-resistant TB strains resistant to the fluoroquinolones and streptomycin had significantly better initial and long-term outcomes, compared with 10 patients with extensively drug-resistant TB.
Bibliografie:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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ISSN:1537-6591
1537-6591
DOI:10.1086/597010