Multidrug-resistant tuberculosis (TB) resistant to fluoroquinolones and streptomycin but susceptible to second-line injection therapy has a better prognosis than extensively drug-resistant TB

Multidrug-resistant tuberculosis (TB) strains resistant to the fluoroquinolones and streptomycin but susceptible to second-line injection treatment would not be defined as extensively drug-resistant TB. In a cohort of 174 patients with multidrug-resistant TB, we demonstrated that 12 patients with mu...

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Vydané v:	Clinical infectious diseases Ročník 48; číslo 5; s. e50
Hlavní autori:	Chan, Edward D, Strand, Matthew J, Iseman, Michael D
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.03.2009
Predmet:	Antitubercular Agents - therapeutic use Cohort Studies Extensively Drug-Resistant Tuberculosis - diagnosis Extensively Drug-Resistant Tuberculosis - drug therapy Fluoroquinolones - therapeutic use Humans Prognosis Streptomycin - therapeutic use Treatment Outcome Tuberculosis, Multidrug-Resistant - diagnosis Tuberculosis, Multidrug-Resistant - drug therapy
ISSN:	1537-6591, 1537-6591
On-line prístup:	Zistit podrobnosti o prístupe
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Popis
Shrnutí:	Multidrug-resistant tuberculosis (TB) strains resistant to the fluoroquinolones and streptomycin but susceptible to second-line injection treatment would not be defined as extensively drug-resistant TB. In a cohort of 174 patients with multidrug-resistant TB, we demonstrated that 12 patients with multidrug-resistant TB strains resistant to the fluoroquinolones and streptomycin had significantly better initial and long-term outcomes, compared with 10 patients with extensively drug-resistant TB.
Bibliografia:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	1537-6591 1537-6591
DOI:	10.1086/597010