Brain Hypoxia Is Associated With Short-term Outcome After Severe Traumatic Brain Injury Independently of Intracranial Hypertension and Low Cerebral Perfusion Pressure

Abstract BACKGROUND Brain hypoxia (BH) can aggravate outcome after severe traumatic brain injury (TBI). Whether BH or reduced brain oxygen (Pbto2) is an independent outcome predictor or a marker of disease severity is not fully elucidated. OBJECTIVE To analyze the relationship between Pbto2, intracr...

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Bibliographic Details
Published in:	Neurosurgery Vol. 69; no. 5; pp. 1037 - 1045
Main Authors:	Oddo, Mauro, Levine, Joshua M., Mackenzie, Larami, Frangos, Suzanne, Feihl, François, Kasner, Scott E., Katsnelson, Michael, Pukenas, Bryan, Macmurtrie, Eileen, Maloney-Wilensky, Eileen, Kofke, W. Andrew, LeRoux, Peter D.
Format:	Journal Article
Language:	English
Published:	Hagerstown, MD Oxford University Press 01.11.2011 Lippincott Williams & Wilkins Wolters Kluwer Health, Inc
Subjects:	Adult Biological and medical sciences Brain Injuries - complications Brain Injuries - mortality Cerebrovascular Circulation - physiology Cerebrovascular Disorders - etiology Cerebrovascular Disorders - mortality Female Humans Hypertension Hypotension - etiology Hypotension - mortality Hypoxia Hypoxia, Brain - etiology Hypoxia, Brain - mortality Intracranial Pressure - physiology Male Medical sciences Middle Aged Neurosurgery Prospective Studies Retrospective Studies Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Time Factors Traumatic brain injury Young Adult Indepedent predictor Intracranial Pressure Traumatic brain injury Outcome Cerebral perfusion pressure Brain tissue oxygen pressure Brain hypoxia Short term Oxygen Nervous system diseases Prognosis Intracranial hypertension Intracranial pressure Cerebral disorder Encephalon Surgery Central nervous system disease Low pressure Hypoxia Head trauma Oxygen pressure
ISSN:	0148-396X, 1524-4040, 1524-4040
Online Access:	Get full text
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