Liver Transplant for Cholangiocarcinoma

Liver transplant (LT) for perihilar cholangiocarcinoma (CCA) offers an opportunity for survival among patients with early-stage but anatomically unresectable disease. The 5-year survival rate after LT is 65% to 70%, higher among patients with primary sclerosing cholangitis, who are often diagnosed e...

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Vydáno v:Gastroenterology clinics of North America Ročník 47; číslo 2; s. 267
Hlavní autoři: Zamora-Valdes, Daniel, Heimbach, Julie K
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 01.06.2018
Témata:
Liver cancer
Neoadjuvant radiotherapy
Hilar cholangiocarcinoma
Intrahepatic cholangiocarcinoma
Liver transplantation
ISSN:1558-1942, 1558-1942
On-line přístup:Zjistit podrobnosti o přístupu
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Shrnutí:Liver transplant (LT) for perihilar cholangiocarcinoma (CCA) offers an opportunity for survival among patients with early-stage but anatomically unresectable disease. The 5-year survival rate after LT is 65% to 70%, higher among patients with primary sclerosing cholangitis, who are often diagnosed earlier, and lower among patients with de novo CCA. The results of LT for hilar CCA, along with recent limited data suggesting favorable survival among patients with very early intrahepatic CCA (ICC), have reignited interest in the subject. This article discusses LT following neoadjuvant therapy for CCA and the early data on LT alone for ICC.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ObjectType-Review-3
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ISSN:1558-1942
1558-1942
DOI:10.1016/j.gtc.2018.01.002