Quantitative Whole Genome Sequencing of Circulating Tumor Cells Enables Personalized Combination Therapy of Metastatic Cancer

Much effort has been dedicated to developing circulating tumor cells (CTC) as a noninvasive cancer biopsy, but with limited success as yet. In this study, we combine a method for isolation of highly pure CTCs using immunomagnetic enrichment/fluorescence-activated cell sorting with advanced whole gen...

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Vydáno v:	Cancer research (Chicago, Ill.) Ročník 77; číslo 16; s. 4530
Hlavní autoři:	Gulbahce, Natali, Magbanua, Mark Jesus M, Chin, Robert, Agarwal, Misha R, Luo, Xuhao, Liu, Jia, Hayden, Daniel M, Mao, Qing, Ciotlos, Serban, Li, Zhenyu, Chen, Yanxiang, Chen, Xingpeng, Li, Yuxiang, Zhang, Rebecca Yu, Lee, Katharine, Tearle, Rick, Park, Emily, Drmanac, Snezana, Rugo, Hope S, Park, John W, Drmanac, Radoje, Peters, Brock A
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 15.08.2017
Témata:	Female Genomics - methods Humans Middle Aged Neoplasm Metastasis Neoplasms - drug therapy Neoplastic Cells, Circulating - metabolism Neoplastic Cells, Circulating - pathology
ISSN:	1538-7445, 1538-7445
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