Quantitative Whole Genome Sequencing of Circulating Tumor Cells Enables Personalized Combination Therapy of Metastatic Cancer

Much effort has been dedicated to developing circulating tumor cells (CTC) as a noninvasive cancer biopsy, but with limited success as yet. In this study, we combine a method for isolation of highly pure CTCs using immunomagnetic enrichment/fluorescence-activated cell sorting with advanced whole gen...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Jg. 77; H. 16; S. 4530
Hauptverfasser:	Gulbahce, Natali, Magbanua, Mark Jesus M, Chin, Robert, Agarwal, Misha R, Luo, Xuhao, Liu, Jia, Hayden, Daniel M, Mao, Qing, Ciotlos, Serban, Li, Zhenyu, Chen, Yanxiang, Chen, Xingpeng, Li, Yuxiang, Zhang, Rebecca Yu, Lee, Katharine, Tearle, Rick, Park, Emily, Drmanac, Snezana, Rugo, Hope S, Park, John W, Drmanac, Radoje, Peters, Brock A
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 15.08.2017
Schlagworte:	Female Genomics - methods Humans Middle Aged Neoplasm Metastasis Neoplasms - drug therapy Neoplastic Cells, Circulating - metabolism Neoplastic Cells, Circulating - pathology
ISSN:	1538-7445, 1538-7445
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