Targeted Treatment of Head and Neck (Pre)Cancer: Preclinical Target Identification and Development of Novel Therapeutic Applications

Head and neck squamous cell carcinomas (HNSCC) develop in the mucosal lining of the upper-aerodigestive tract. In carcinogen-induced HNSCC, tumors emerge from premalignant mucosal changes characterized by tumor-associated genetic alterations, also coined as ‘fields’ that are occasionally visible as...

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Bibliographic Details
Published in:	Cancers Vol. 13; no. 11; p. 2774
Main Authors:	van Harten, Anne M., Brakenhoff, Ruud H.
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 03.06.2021 MDPI
Subjects:	Addictions Alcohol Biomarkers Cancer therapies Carcinogens Cell cycle Chemotherapy Diagnosis DNA damage Head & neck cancer Head and neck carcinoma Human papillomavirus Immune checkpoint inhibitors Immune system Immunotherapy Larynx Lethality Leukokeratosis Medical prognosis Mitochondrial DNA Mucosa Mutation Oral cavity Patients Pharynx Radiation therapy Review Squamous cell carcinoma Surgery Therapeutic applications Tumors
ISSN:	2072-6694, 2072-6694
Online Access:	Get full text
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