Microwave assisted extraction of phenolic compounds from four economic brown macroalgae species and evaluation of their antioxidant activities and inhibitory effects on α-amylase, α-glucosidase, pancreatic lipase and tyrosinase

Four economically important brown algae species (Ascophyllum nodosum, Laminaria japonica, Lessonia trabeculate and Lessonia nigrecens) were investigated for phenolic compound extraction and evaluated for their antioxidant, anti-hyperglycemic, and pancreatic lipase and tyrosinase inhibition activitie...

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Vydáno v:	Food research international Ročník 113; s. 288 - 297
Hlavní autoři:	Yuan, Yuan, Zhang, Jian, Fan, Jiajun, Clark, James, Shen, Peili, Li, Yiqiang, Zhang, Chengsheng
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Canada Elsevier Ltd 01.11.2018
Témata:	2,2-diphenyl-1-picrylhydrazyl acarbose alpha-amylase alpha-glucosidase ambient temperature Anti-hyperglycaemic activity Antioxidant antioxidant activity Antioxidants - chemistry Antioxidants - pharmacology Ascophyllum nodosum Brown macroalgae Chemical Fractionation - methods enzyme inhibition Enzyme Inhibitors - chemistry Enzyme Inhibitors - pharmacology free radical scavengers glycemic effect Glycoside Hydrolase Inhibitors - chemistry Glycoside Hydrolase Inhibitors - pharmacology Lessonia Lipase - antagonists & inhibitors macroalgae Microwave assisted extraction (MAE) microwave treatment Microwaves Monophenol Monooxygenase - antagonists & inhibitors Pancreatic lipase inhibition activity Phaeophyceae - chemistry Phenolic compounds Plant Extracts - chemistry Plant Extracts - pharmacology Saccharina japonica Seaweed - chemistry triacylglycerol lipase Tyrosinase inhibition activity Brown macroalgae Tyrosinase inhibition activity Anti-hyperglycaemic activity Phenolic compounds Antioxidant Pancreatic lipase inhibition activity Microwave assisted extraction (MAE)
ISSN:	0963-9969, 1873-7145, 1873-7145
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Shrnutí:	Four economically important brown algae species (Ascophyllum nodosum, Laminaria japonica, Lessonia trabeculate and Lessonia nigrecens) were investigated for phenolic compound extraction and evaluated for their antioxidant, anti-hyperglycemic, and pancreatic lipase and tyrosinase inhibition activities. Microwave assisted extraction (MAE) at 110 °C for 15 min resulted in both higher crude yield and higher total phenolic content (TPC) for all algae species compared with those obtained by conventional extraction at room temperature for 4 h, and Ascophyllum nodosum yielded the highest TPC. Antioxidant tests indicated that extracts acquired by MAE from four species all exhibited higher DPPH, ABTS free radical scavenging ability and reducing power than the conventional method. The extract of Lessonia trabeculate exhibited good α-amylase, α-glucosidase, pancreatic lipase, and tyrosinase inhibition activities, and the MAE extract showed even better α-glucosidase inhibitory activity than acarbose. [Display omitted] •Polyphenols were effectively extracted by microwave assisted extraction.•Extracts of Ascophyllum nodosum showed good antioxidant activities.•Four enzymes were inhibited in vitro by brown macroalgae polyphenol extracts.•Extracts of Lessonia trabeculate showed inhibitory activities in all four enzymes.•Extracts of Lessonia trabeculate had better α-glucosidase inhibition than acarbose.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0963-9969 1873-7145 1873-7145
DOI:	10.1016/j.foodres.2018.07.021