Classification of Blood Culture Isolates Into Contaminants and Pathogens on the Basis of Clinical and Laboratory Data

The multisite community-based study, Aetiology of Neonatal Infection in South Asia (ANISA), uses blood culture as the gold standard for identifying the etiology of neonatal infection. Considering the importance of this age-old diagnostic tool and the risk of contamination, ANISA has employed rigorou...

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Vydáno v:The Pediatric infectious disease journal Ročník 35; číslo 5 Suppl 1; s. S52
Hlavní autoři: Hossain, Belal, Weber, Martin W, Hamer, Davidson H, Hibberd, Patricia L, Ahmed, A S M Nawshad Uddin, Marzan, Mahfuza, Islam, Maksuda, Connor, Nicholas E, Islam, Mohammad Shahidul, Zaidi, Anita K, Baqui, Abdullah H, Bhutta, Zulfiqar A, Qureshi, Shahida M, Rafiqullah, Iftekhar, McGee, Lesley, Saha, Samir K
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 01.05.2016
Témata:
Asia, Western - epidemiology
Bacteremia - epidemiology
Bacteremia - etiology
Bacteria - classification
Bacteria - isolation & purification
Blood Culture - methods
Child, Preschool
Diagnostic Errors
Diagnostic Tests, Routine
Female
Humans
Infant
Infant, Newborn
Male
Neonatal Sepsis - epidemiology
Neonatal Sepsis - etiology
ISSN:1532-0987, 1532-0987
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Shrnutí:The multisite community-based study, Aetiology of Neonatal Infection in South Asia (ANISA), uses blood culture as the gold standard for identifying the etiology of neonatal infection. Considering the importance of this age-old diagnostic tool and the risk of contamination, ANISA has employed rigorous measures to prevent contamination at all stages of blood collection, processing and culture. Because contamination may still occur, an independent expert group evaluates the routinely collected clinical and laboratory data to determine whether a blood culture isolate is a contaminant or a true pathogen. This article describes the methodology used by ANISA to determine whether a blood culture isolate is likely to be a true pathogen or a contaminant in neonatal sepsis.
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ISSN:1532-0987
1532-0987
DOI:10.1097/INF.0000000000001107