Adding Celecoxib With or Without Zoledronic Acid for Hormone-Naïve Prostate Cancer: Long-Term Survival Results From an Adaptive, Multiarm, Multistage, Platform, Randomized Controlled Trial

Purpose Systemic Therapy for Advanced or Metastatic Prostate Cancer: Evaluation of Drug Efficacy is a randomized controlled trial using a multiarm, multistage, platform design. It recruits men with high-risk, locally advanced or metastatic prostate cancer who were initiating long-term hormone therap...

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Veröffentlicht in:	Journal of clinical oncology Jg. 35; H. 14; S. 1530
Hauptverfasser:	Mason, Malcolm D, Clarke, Noel W, James, Nicholas D, Dearnaley, David P, Spears, Melissa R, Ritchie, Alastair W S, Attard, Gerhardt, Cross, William, Jones, Rob J, Parker, Christopher C, Russell, J Martin, Thalmann, George N, Schiavone, Francesca, Cassoly, Estelle, Matheson, David, Millman, Robin, Rentsch, Cyrill A, Barber, Jim, Gilson, Clare, Ibrahim, Azman, Logue, John, Lydon, Anna, Nikapota, Ashok D, O'Sullivan, Joe M, Porfiri, Emilio, Protheroe, Andrew, Srihari, Narayanan Nair, Tsang, David, Wagstaff, John, Wallace, Jan, Walmsley, Catherine, Parmar, Mahesh K B, Sydes, Matthew R
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 10.05.2017
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Cause of Death Celecoxib - administration & dosage Diphosphonates - administration & dosage Disease-Free Survival Early Termination of Clinical Trials Follow-Up Studies Gonadotropin-Releasing Hormone - agonists Gonadotropin-Releasing Hormone - antagonists & inhibitors Humans Imidazoles - administration & dosage Lymphatic Metastasis Male Middle Aged Orchiectomy Proportional Hazards Models Prostate-Specific Antigen - blood Prostatic Neoplasms - drug therapy Prostatic Neoplasms - pathology Prostatic Neoplasms - surgery Survival Rate Time Factors Zoledronic Acid
ISSN:	1527-7755, 1527-7755
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